USP54 and RAMAC

Data Source:
BioGRID (two hybrid)

		USP54	RAMAC
Description		ubiquitin specific peptidase 54	RNA guanine-7 methyltransferase activating subunit
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm MRNA Cap Binding Complex MRNA Cap Methyltransferase Complex
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding	RNA Binding Protein Binding Enzyme Activator Activity
	Biological Process	Protein Deubiquitination Protein Phosphopantetheinylation	7-methylguanosine MRNA Capping Methylation Recruitment Of MRNA Capping Enzyme To RNA Polymerase II Holoenzyme Complex Regulation Of Catalytic Activity RNA 5'-cap (guanine-N7)-methylation
Pathways
Drugs
Diseases
GWAS		Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		88 interacting genes: ANKRD11 ANKS1A ARMC7 ATN1 ATXN1 ATXN1L ATXN7L2 BFSP2 BHLHE40 CARD10 CCDC13 CCDC24 CCNK CDC23 CHCHD2 CHERP CHMP1B CHMP2A CHMP2B CHMP4C CSTF2 CYSRT1 DMRT3 DOK6 DTX2 EIF4E2 EPM2AIP1 EXOC8 FAM124B FBXO17 FNDC3B FOXI1 GCM2 HGS HNF1B HNRNPF HOXC8 IGFN1 INSC KCTD9 LMO3 LNX1 MED25 MID2 NUDT22 NXT2 OIP5 OTX1 PCSK5 PHF1 PLA2G6 PLAC8 PLEKHN1 POLR1C PRDM6 PRKAB2 PRR35 QRICH1 RACK1 RAMAC RBPMS2 RHOBTB3 RNF208 SEC24A SHARPIN SHC3 SMARCD1 SMYD1 SNRPB SS18L1 STK16 TBX6 TCEA2 TEKT5 TENT5B TFAP2D TLE5 TNS2 TOLLIP TSEN15 TSSK3 TTC19 UBC USP2 VENTX ZCCHC14 ZNF148 ZNF76	47 interacting genes: AKAP8L BAG4 BPIFA1 C10orf55 CYSRT1 DAB1 DAZAP2 DMRTB1 FAM168B FOXI1 GOLGA2 HNRNPH1 HNRNPK INCA1 KRT15 KRT31 KRT33B KRTAP1-3 KRTAP8-1 LZTS2 MAGED1 MAPK1IP1L NAF1 OXER1 PEA15 PLSCR1 PLSCR4 POU2AF1 PRR3 PSMA3 RBMX RBMY1F RBPMS RHOXF2 RINT1 RNMT SF3B4 SNRPC TEKT3 TEKT4 TNS2 TRIM23 TRIM27 TRIM42 USP54 VPS37C WWOX
Entrez ID		159195	83640
HPRD ID		15641	12845
Ensembl ID		ENSG00000166348	ENSG00000169612
Uniprot IDs		B7Z7X1 Q70EL1	Q9BTL3
PDB IDs			5E8J
Enriched GO Terms of Interacting Partners?
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