ING5 and RCOR3

Data Source:
BioGRID (two hybrid)

		ING5	RCOR3
Description		inhibitor of growth family member 5	REST corepressor 3
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GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm Chromosome MOZ/MORF Histone Acetyltransferase Complex	Histone Deacetylase Complex Nucleoplasm Transcription Regulator Complex Cytosol
	Molecular Function	Chromatin Binding Protein Binding Methylated Histone Binding Metal Ion Binding	Transcription Corepressor Activity Protein Binding
	Biological Process	DNA Replication Protein Acetylation Negative Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Histone H4 Acetylation Histone H3-K14 Acetylation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Growth Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Apoptotic Signaling Pathway	Regulation Of Transcription By RNA Polymerase II Histone Deacetylation Negative Regulation Of Transcription, DNA-templated
Pathways		HATs acetylate histones Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS		Asthma ( 31959851) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Platelet distribution width ( 32888494)	Plateletcrit ( 32888494)
Interacting Genes		47 interacting genes: APC APLP1 ARFIP2 BARD1 BEX3 BRPF1 C3orf62 CBY2 CCDC33 CCHCR1 CDCA7L CDK2 CDKN1A CEP126 CEP44 DEUP1 EP300 FAM118B GCSH GGA1 GRIPAP1 HAP1 HGS HTT ICA1 IKZF3 JADE2 KRT40 KRTAP10-7 KXD1 MBIP MCM6 MEST NAV2 ODF2 PCM1 PRMT5 RCOR3 SMARCE1 SUOX TADA3 TAF1D THAP6 TP53 TRIML2 VIM WASF1	74 interacting genes: ABI1 ANKRD11 APP BHLHB9 BORCS6 CBY2 CCDC102B CCDC106 CCHCR1 CDR2 CEP55 CEP63 CEP70 EFHC2 FAM81A FSD2 GKAP1 GLRX3 GOLGA2 GRIPAP1 GSE1 HAUS3 HMBOX1 HOOK2 HSF2BP ICA1L IKZF3 ING5 ISY1-RAB43 KDM1A KRT15 KRT18 KRT19 KRT24 KRT27 KRT31 KRT40 KRT75 LCA5 LHX3 LUZP4 LZTS2 MAGEA6 MCC MESD MID2 MIPOL1 MTUS2 NDUFB7 NECAB2 NINL NRDE2 NUTM1 PHF19 PHF21B PIH1D1 PRDM14 PTTG2 STN1 SUMO2 TFIP11 TRAF1 TRAF2 TRIM27 TRIM42 TRIM54 TSGA10 TULP3 TXLNA USHBP1 VAX1 YWHAQ ZNF383 ZNF688
Entrez ID		84289	55758
HPRD ID		16348	08338
Ensembl ID		ENSG00000168395	ENSG00000117625
Uniprot IDs		A0A1B0GW41 Q8WYH8	Q9P2K3
PDB IDs		3C6W 5ME8 5MTO	4CZZ
Enriched GO Terms of Interacting Partners?
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