ING5 and JADE2

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology)

		ING5	JADE2
Description		inhibitor of growth family member 5	jade family PHD finger 2
Image			No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm Chromosome MOZ/MORF Histone Acetyltransferase Complex	Histone Acetyltransferase Complex Nucleoplasm Extracellular Exosome
	Molecular Function	Chromatin Binding Protein Binding Methylated Histone Binding Metal Ion Binding	Protein Binding Transferase Activity Metal Ion Binding
	Biological Process	DNA Replication Protein Acetylation Negative Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Histone H4 Acetylation Histone H3-K14 Acetylation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Growth Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Apoptotic Signaling Pathway	Protein Ubiquitination Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation
Pathways		HATs acetylate histones Regulation of TP53 Activity through Acetylation	HATs acetylate histones
Drugs
Diseases
GWAS		Asthma ( 31959851) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Platelet distribution width ( 32888494)	Adult body size ( 32376654) Age at first birth ( 27798627) Body mass index ( 28892062) Brain morphology (MOSTest) ( 32665545) Coffee consumption ( 31046077) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hand grip strength ( 29691431) Household income (MTAG) ( 31844048) Mental health study participation (completed survey) ( 31263887) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Platelet distribution width ( 27863252) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 28869590) White blood cell count ( 32888494)
Interacting Genes		47 interacting genes: APC APLP1 ARFIP2 BARD1 BEX3 BRPF1 C3orf62 CBY2 CCDC33 CCHCR1 CDCA7L CDK2 CDKN1A CEP126 CEP44 DEUP1 EP300 FAM118B GCSH GGA1 GRIPAP1 HAP1 HGS HTT ICA1 IKZF3 JADE2 KRT40 KRTAP10-7 KXD1 MBIP MCM6 MEST NAV2 ODF2 PCM1 PRMT5 RCOR3 SMARCE1 SUOX TADA3 TAF1D THAP6 TP53 TRIML2 VIM WASF1	16 interacting genes: CBX8 CDCA7L CSNK2A1 FBXO7 GAS2L2 GORASP2 H3-4 ING4 ING5 MEAF6 PACSIN1 SASH1 ZBTB3 ZBTB5 ZNF417 ZNF496
Entrez ID		84289	23338
HPRD ID		16348	15124
Ensembl ID		ENSG00000168395	ENSG00000043143
Uniprot IDs		A0A1B0GW41 Q8WYH8	A0A0C4DFT8 B3KPL2 B4DFY8 G3XAA4 Q9NQC1
PDB IDs		3C6W 5ME8 5MTO
Enriched GO Terms of Interacting Partners?
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