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ING5 and THAP6
Data Source:
BioGRID
(two hybrid)
ING5
THAP6
Description
inhibitor of growth family member 5
THAP domain containing 6
Image
No pdb structure
GO Annotations
Cellular Component
Histone Acetyltransferase Complex
Nucleus
Nucleoplasm
Chromosome
MOZ/MORF Histone Acetyltransferase Complex
Microtubule Cytoskeleton
Molecular Function
Chromatin Binding
Protein Binding
Methylated Histone Binding
Metal Ion Binding
DNA Binding
Protein Binding
Metal Ion Binding
Biological Process
DNA Replication
Protein Acetylation
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Apoptotic Process
Histone H3 Acetylation
Histone H4 Acetylation
Histone H3-K14 Acetylation
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Growth
Regulation Of Signal Transduction By P53 Class Mediator
Positive Regulation Of Apoptotic Signaling Pathway
Pathways
HATs acetylate histones
Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS
Asthma (
31959851
)
Asthma (adult onset) (
31036433
)
Asthma (childhood onset) (
31036433
)
Hematocrit (
32888494
)
Hemoglobin (
32888494
)
Hemoglobin levels (
32327693
)
Platelet distribution width (
32888494
)
Mean platelet volume (
32888494
)
Interacting Genes
47 interacting genes:
APC
APLP1
ARFIP2
BARD1
BEX3
BRPF1
C3orf62
CBY2
CCDC33
CCHCR1
CDCA7L
CDK2
CDKN1A
CEP126
CEP44
DEUP1
EP300
FAM118B
GCSH
GGA1
GRIPAP1
HAP1
HGS
HTT
ICA1
IKZF3
JADE2
KRT40
KRTAP10-7
KXD1
MBIP
MCM6
MEST
NAV2
ODF2
PCM1
PRMT5
RCOR3
SMARCE1
SUOX
TADA3
TAF1D
THAP6
TP53
TRIML2
VIM
WASF1
17 interacting genes:
ADAMTSL4
AP1M1
CABP2
HSF2BP
INCA1
ING5
KANK2
KRTAP10-7
LMO2
MAD2L2
NTAQ1
PICK1
PSMB1
SDCBP2
TNPO2
ZGPAT
ZNF655
Entrez ID
84289
152815
HPRD ID
16348
15499
Ensembl ID
ENSG00000168395
ENSG00000174796
Uniprot IDs
A0A1B0GW41
Q8WYH8
A0A024RDF9
Q8TBB0
PDB IDs
3C6W
5ME8
5MTO
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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