ING5 and THAP6

Data Source:
BioGRID (two hybrid)

		ING5	THAP6
Description		inhibitor of growth family member 5	THAP domain containing 6
Image			No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm Chromosome MOZ/MORF Histone Acetyltransferase Complex	Microtubule Cytoskeleton
	Molecular Function	Chromatin Binding Protein Binding Methylated Histone Binding Metal Ion Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	DNA Replication Protein Acetylation Negative Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Histone H4 Acetylation Histone H3-K14 Acetylation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Growth Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Apoptotic Signaling Pathway
Pathways		HATs acetylate histones Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS		Asthma ( 31959851) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Platelet distribution width ( 32888494)	Mean platelet volume ( 32888494)
Interacting Genes		47 interacting genes: APC APLP1 ARFIP2 BARD1 BEX3 BRPF1 C3orf62 CBY2 CCDC33 CCHCR1 CDCA7L CDK2 CDKN1A CEP126 CEP44 DEUP1 EP300 FAM118B GCSH GGA1 GRIPAP1 HAP1 HGS HTT ICA1 IKZF3 JADE2 KRT40 KRTAP10-7 KXD1 MBIP MCM6 MEST NAV2 ODF2 PCM1 PRMT5 RCOR3 SMARCE1 SUOX TADA3 TAF1D THAP6 TP53 TRIML2 VIM WASF1	17 interacting genes: ADAMTSL4 AP1M1 CABP2 HSF2BP INCA1 ING5 KANK2 KRTAP10-7 LMO2 MAD2L2 NTAQ1 PICK1 PSMB1 SDCBP2 TNPO2 ZGPAT ZNF655
Entrez ID		84289	152815
HPRD ID		16348	15499
Ensembl ID		ENSG00000168395	ENSG00000174796
Uniprot IDs		A0A1B0GW41 Q8WYH8	A0A024RDF9 Q8TBB0
PDB IDs		3C6W 5ME8 5MTO
Enriched GO Terms of Interacting Partners?
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