SLC10A2 and TMEM222

Data Source:
BioGRID (two hybrid)

		SLC10A2	TMEM222
Description		solute carrier family 10 member 2	transmembrane protein 222
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane	Integral Component Of Membrane
	Molecular Function	Protein Binding Bile Acid:sodium Symporter Activity	Protein Binding
	Biological Process	Sodium Ion Transport Bile Acid And Bile Salt Transport Transmembrane Transport
Pathways		Recycling of bile acids and salts
Drugs		Volixibat
Diseases		Primary bile acid malabsorption
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) epithelial cell adhesion molecule levels ( 25147954) Esophageal cancer (alcohol interaction) ( 22960999) Gallstone disease ( 30504769) Late-onset Alzheimer's disease ( 27770636) Metabolite levels ( 23823483) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377) Response to quetiapine in schizophrenia ( 29503163) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Alanine aminotransferase levels ( 31219225)
Interacting Genes		10 interacting genes: C3orf52 CCL4L2 CTXN3 EFNA5 IFITM3 NRM PSENEN TEX264 TMEM222 UPK1B	38 interacting genes: ABHD16A AQP6 BIK BSCL2 CD79A CLDN5 CLRN1 COMT CRB3 CREB3 CREB3L1 EBP ELOVL4 ERG28 ERGIC3 EVI2B FAM174A FAM209A HIBADH HSD17B13 KIR2DL3 LMNA LRRC59 NCR3LG1 PEX12 PRSS23 PTGES RETREG3 RNASEK SLC10A1 SLC10A2 SSMEM1 STX1A TMEM14B TMEM35A TMPRSS2 TMX2 ZDHHC15
Entrez ID		6555	84065
HPRD ID		03189	13167
Ensembl ID		ENSG00000125255	ENSG00000186501
Uniprot IDs		Q12908	Q9H0R3
PDB IDs
Enriched GO Terms of Interacting Partners?
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