CASP5 and PPHLN1

Data Source:
HPRD (in vitro)

		CASP5	PPHLN1
Description		caspase 5	periphilin 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm NLRP1 Inflammasome Complex	Nucleoplasm Chromosome Golgi Apparatus Cytosol
	Molecular Function	Cysteine-type Endopeptidase Activity Protein Binding Cysteine-type Peptidase Activity Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Cysteine-type Endopeptidase Activity Involved In Execution Phase Of Apoptosis	RNA Binding Protein Binding
	Biological Process	Proteolysis Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Substantia Nigra Development Regulation Of Apoptotic Process Regulation Of Inflammatory Response Cellular Response To Mechanical Stimulus Apoptotic Signaling Pathway Execution Phase Of Apoptosis	Keratinization Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of DNA Methylation-dependent Heterochromatin Assembly Protein Localization To Heterochromatin
Pathways
Drugs
Diseases
GWAS			Body size at age 10 ( 32376654) Coronary artery disease ( 29212778) Diastolic blood pressure ( 30224653) Refractive error ( 32231278)
Interacting Genes		3 interacting genes: MAX NLRP1 PPHLN1	25 interacting genes: APP BCL2L1 BRCA1 CASP5 CCDC57 CDC37 CDK6 CLK1 FBXO7 ITGB1BP2 MTUS2 NAGK PAXIP1 PPL SEPTIN8 SNCAIP SQSTM1 SRPK2 TGM2 TOMM20 TOPBP1 TP53BP2 TSGA10 UFD1 VIM
Entrez ID		838	51535
HPRD ID		04048	10488
Ensembl ID		ENSG00000137757	ENSG00000134283
Uniprot IDs		P51878	Q8NEY8
PDB IDs			6SWG
Enriched GO Terms of Interacting Partners?
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