RILP and VPS36

Data Source:
BioGRID (pull down)

		RILP	VPS36
Description		Rab interacting lysosomal protein	vacuolar protein sorting 36 homolog
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GO Annotations	Cellular Component	Cytoplasm Lysosome Lysosomal Membrane Late Endosome Cytosol Phagocytic Vesicle Membrane Late Endosome Membrane Protein-containing Complex Ciliary Basal Body	ESCRT II Complex Nucleus Endosome Cytosol Late Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding Small GTPase Binding Protein Dimerization Activity Dynein Light Intermediate Chain Binding	Protein Binding Protein C-terminus Binding Phosphatidylinositol-3-phosphate Binding Ubiquitin Binding
	Biological Process	Endosome To Lysosome Transport Regulation Of Multivesicular Body Size Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Endosome Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Protein Catabolic Process Early Endosome To Late Endosome Transport Positive Regulation Of Protein Catabolic Process Cilium Assembly Intralumenal Vesicle Formation	Endosomal Transport Macroautophagy Multivesicular Body Assembly Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Pathways		MHC class II antigen presentation	Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events
Drugs
Diseases
GWAS			Lewy body disease ( 25188341)
Interacting Genes		12 interacting genes: KPNA2 LDB2 RAB34 RAB7A RCHY1 SNF8 VPS11 VPS16 VPS18 VPS36 VPS39 VPS41	7 interacting genes: CHMP6 RILP SNF8 SPRY2 TSG101 UBC VPS25
Entrez ID		83547	51028
HPRD ID		09706	12620
Ensembl ID		ENSG00000167705	ENSG00000136100
Uniprot IDs		Q96NA2	Q86VN1
PDB IDs		1YHN	2HTH 2ZME 3CUQ
Enriched GO Terms of Interacting Partners?
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