RILP and RAB34

Data Source:
HPRD (two hybrid, in vitro)

		RILP	RAB34
Description		Rab interacting lysosomal protein	RAB34, member RAS oncogene family
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Lysosomal Membrane Late Endosome Cytosol Phagocytic Vesicle Membrane Late Endosome Membrane Protein-containing Complex Ciliary Basal Body	Golgi Apparatus Golgi Stack Cilium Phagocytic Vesicle Membrane Vesicle Golgi Cisterna Ruffle Membrane Phagocytic Vesicle Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding Small GTPase Binding Protein Dimerization Activity Dynein Light Intermediate Chain Binding	GTPase Activity Protein Binding GTP Binding GTP-dependent Protein Binding Small GTPase Binding
	Biological Process	Endosome To Lysosome Transport Regulation Of Multivesicular Body Size Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Endosome Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Protein Catabolic Process Early Endosome To Late Endosome Transport Positive Regulation Of Protein Catabolic Process Cilium Assembly Intralumenal Vesicle Formation	Endocytosis Antigen Processing And Presentation Cell Projection Organization Lysosome Localization Golgi To Plasma Membrane Protein Transport Macropinocytosis Positive Regulation Of Smoothened Signaling Pathway Protein Localization To Plasma Membrane Phagosome Maturation Phagosome-lysosome Fusion
Pathways		MHC class II antigen presentation	RAB geranylgeranylation
Drugs
Diseases
GWAS			Urate levels in lean individuals ( 25811787)
Interacting Genes		12 interacting genes: KPNA2 LDB2 RAB34 RAB7A RCHY1 SNF8 VPS11 VPS16 VPS18 VPS36 VPS39 VPS41	8 interacting genes: CA8 RABGAP1L RALA RILP SMAD1 SMAD2 SMAD4 TGFBR1
Entrez ID		83547	83871
HPRD ID		09706	06701
Ensembl ID		ENSG00000167705	ENSG00000109113
Uniprot IDs		Q96NA2	A0A024QZ68 B4DNC0 E7ES60 P0DI83 Q96PJ7 Q9BZG1
PDB IDs		1YHN
Enriched GO Terms of Interacting Partners?
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