RILP and VPS16

Data Source:
BioGRID (pull down)

		RILP	VPS16
Description		Rab interacting lysosomal protein	VPS16 core subunit of CORVET and HOPS complexes
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GO Annotations	Cellular Component	Cytoplasm Lysosome Lysosomal Membrane Late Endosome Cytosol Phagocytic Vesicle Membrane Late Endosome Membrane Protein-containing Complex Ciliary Basal Body	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Clathrin-coated Vesicle Axon HOPS Complex Late Endosome Membrane Neuronal Cell Body Recycling Endosome
	Molecular Function	Protein Binding Small GTPase Binding Protein Dimerization Activity Dynein Light Intermediate Chain Binding	Actin Binding Protein Binding Actin Filament Binding
	Biological Process	Endosome To Lysosome Transport Regulation Of Multivesicular Body Size Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Endosome Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Protein Catabolic Process Early Endosome To Late Endosome Transport Positive Regulation Of Protein Catabolic Process Cilium Assembly Intralumenal Vesicle Formation	Intracellular Protein Transport Vacuole Organization Endosome To Lysosome Transport Endosomal Transport Vacuole Fusion, Non-autophagic Autophagosome Maturation
Pathways		MHC class II antigen presentation
Drugs
Diseases
GWAS			Lymphocyte percentage of white cells ( 32888494) Metabolite levels ( 23823483)
Interacting Genes		12 interacting genes: KPNA2 LDB2 RAB34 RAB7A RCHY1 SNF8 VPS11 VPS16 VPS18 VPS36 VPS39 VPS41	17 interacting genes: AKTIP EXOC8 FBXO7 GNG13 HOOK1 HOOK2 HOOK3 MON1B RAB7A RILP STX1A STX7 UVRAG VPS11 VPS18 VPS33A ZNF417
Entrez ID		83547	64601
HPRD ID		09706	12259
Ensembl ID		ENSG00000167705	ENSG00000215305
Uniprot IDs		Q96NA2	Q9H269
PDB IDs		1YHN	4BX9
Enriched GO Terms of Interacting Partners?
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