H2AC16 and BRD7

Data Source:
HPRD (in vitro)

		H2AC16	BRD7
Description		H2A clustered histone 16	bromodomain containing 7
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GO Annotations	Cellular Component	Nucleosome Nucleus Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	DNA Binding Protein Binding Enzyme Binding Protein Heterodimerization Activity	Transcription Regulatory Region Sequence-specific DNA Binding P53 Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Histone Binding Lysine-acetylated Histone Binding
	Biological Process	Chromatin Silencing Biological_process	Regulation Of Transcription By RNA Polymerase II Cell Cycle Negative Regulation Of Cell Population Proliferation Wnt Signaling Pathway Positive Regulation Of Histone Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		HDACs deacetylate histones HATs acetylate histones HATs acetylate histones RMTs methylate histone arginines UCH proteinases Ub-specific processing proteases Metalloprotease DUBs HCMV Early Events HCMV Late Events	Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS			Allergic sensitization ( 30013184) Epilepsy ( 30531953) Liver enzyme levels (alanine transaminase) ( 24124411) Medication use (thyroid preparations) ( 31015401)
Interacting Genes		5 interacting genes: BRD7 CRP GADD45A SAP30 TERF2IP	30 interacting genes: AGR2 BARD1 BHLHE40 BRD3 BTBD2 DVL1 FTH1 H2AC16 H2BC21 H3-3A H3-4 H3C14 H4-16 HAP1 HNRNPUL1 IRF2 LAMA4 LRIF1 MX1 NEFL PAFAH1B3 PARP1 PCBD1 PLEKHF2 PSMD11 PTPN13 RIF1 RPLP1 SERPINB9 TRIM24
Entrez ID		8332	29117
HPRD ID		09103	12531
Ensembl ID		ENSG00000276903	ENSG00000166164
Uniprot IDs		A4FTV9 P0C0S8	Q9NPI1
PDB IDs		4QYL 5KGF 6R0C 6RNY 6X59 6X5A 6XJD 7JO9 7JOA	2I7K 5MQ1 6PPA 6V0Q 6V16 6V17 6V1E 6V1F 6V1H
Enriched GO Terms of Interacting Partners?
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