DYSF and APPL1

  • Data Source:
  • BioGRID (affinity chromatography technology, two hybrid, imaging technique)

DYSF

APPL1

Description dysferlin adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Asthma ( 32296059)
  • Extremely high intelligence ( 29520040)
  • General cognitive ability ( 29844566)
  • Hip circumference adjusted for BMI ( 28552196)
  • Nonalcoholic steatohepatitis-derived hepatocellular carcinoma ( 29385134)
  • PR interval in Tripanosoma cruzi seropositivity ( 24324551)
  • Protein quantitative trait loci ( 18464913)
  • Urate levels in overweight individuals ( 25811787)
Interacting Genes 40 interacting genes: AKAP1 ANKRD1 ANXA1 ANXA2 APPL1 CAPN3 CAV3 CMYA5 COL12A1 COL6A3 DGKD DHX15 DNAJB6 EEF1A1 EEF1G FAM120A GNL3 KARS1 KIF1B MORF4L1 MYBPC1 MYBPC2 MYH3 MYOM1 MYOM2 NPHP3 OPTN OS9 PHF1 PLP1 RNF10 RNF2 SAMHD1 SGCG SLC12A6 SNAPIN TAF1 XIRP2 XRCC6 ZNF23 64 interacting genes: ADI1 ADIPOR1 ADIPOR2 AGL AKT1 AKT2 ANKRD1 APPL2 ATP2A1 BATF3 BIN1 BRWD1 C1QTNF9 CBL CBLB CIPC CMTM4 CTTNBP2 DACT1 DCC DNM2 DOK2 DOK3 DOK7 DPYSL5 DTNA DYSF EGFR FARS2 FSHR GPC3 HDAC2 HSPB1 ID1 INO80E KLF15 KXD1 LUC7L MAGEA9 MAGEC3 MAP3K1 MEOX1 MTA2 MYCBP2 MYH3 PIK3CA PIK3R1 PIK3R2 PLEKHF2 PNMA5 RAB21 RAB5A RBBP7 RHEBL1 RUVBL2 SCAPER SH2D2A SOCS6 SPART TP53 TP53BP2 TRAF2 UBE2O ZNF829
Entrez ID 8291 26060
HPRD ID 04307 05053
Ensembl ID ENSG00000135636 ENSG00000157500
Uniprot IDs O75923 Q9UKG1
PDB IDs 4CAH 4CAI 4IHB 4IQH 2EJ8 2ELA 2ELB 2Q12 2Q13 2Z0N 2Z0O 5C5B
Enriched GO Terms of Interacting Partners?
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