TSSK3 and PLEKHG4

Data Source:
BioGRID (two hybrid)

		TSSK3	PLEKHG4
Description		testis specific serine kinase 3	pleckstrin homology and RhoGEF domain containing G4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Protein Phosphorylation Multicellular Organism Development Spermatogenesis Cell Differentiation Intracellular Signal Transduction	Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS		Pre-treatment viral load in HIV-1 infection ( 31219150)	Blood protein levels ( 29875488 28240269) Heel bone mineral density ( 28869591) Refractive error ( 32231278)
Interacting Genes		67 interacting genes: ADAMTSL4 ARID5A ATP23 C15orf48 C2CD6 C9orf24 CCDC130 CENPN DDIT4L DRG2 ECSIT EFHC2 EYA2 FUT9 GOLGA2 GP2 IKZF3 INCA1 KRT75 KRTAP13-2 KRTAP13-3 LBX1 LHX3 LMO2 LNX1 LZTS2 MBD3L1 MEI4 MRPL28 MSX2 MYOG MYOZ3 NFKBID NME4 OIP5 PBX4 PJA1 PLEKHG4 PPP1R16A PRDM6 RBBP4 RBCK1 REL RIN3 RUSC1 SHISA6 SLAIN1 SMAD4 STAT5B SYNGAP1 TCF4 TCP10L TEPSIN TGM7 TLE5 TRIM35 TRIM50 TRIM54 TRIM9 TRIP6 UROD USP54 VGLL1 VPS52 YPEL3 ZBTB25 ZMYND12	65 interacting genes: A1CF ARHGEF5 ARMC7 BEX2 CCDC120 CCDC187 CDC42 CDKN2C CHIC2 COIL DCUN1D5 DPPA3 DTX2 DUSP13 FAM161A FGD2 GATA3 GCM2 GSTZ1 HCK HOXB9 HOXC8 KRT3 KRT75 MALSU1 MATR3 MDFI METAP1 MSRB3 MTA1 MYEF2 MYOZ1 NATD1 OTX1 PFKFB1 PKP2 PPP1R32 PRPF18 PRPF31 PSMB1 RHOA RIN1 SAXO1 SETD5 SH2D4A SHISA6 SIX1 SMCP SMG9 TBC1D22B TBX18 TEKT3 TENT5D TFAP2D TFG TRIM55 TRIM63 TSSK3 TTC23 USP2 VPS37C ZCCHC14 ZNF148 ZNF319 ZNF648
Entrez ID		81629	25894
HPRD ID		09635	10890
Ensembl ID		ENSG00000162526	ENSG00000196155
Uniprot IDs		Q96PN8	A0A024R6X4 Q58EX7
PDB IDs
Enriched GO Terms of Interacting Partners?
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