PLEKHG4 and CHIC2

Data Source:
BioGRID (two hybrid)

		PLEKHG4	CHIC2
Description		pleckstrin homology and RhoGEF domain containing G4	cysteine rich hydrophobic domain 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Golgi Apparatus Golgi-associated Vesicle Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	Molecular_function Protein Binding
	Biological Process	Regulation Of Catalytic Activity	Biological_process
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 29875488 28240269) Heel bone mineral density ( 28869591) Refractive error ( 32231278)	Blood pressure ( 21909110) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Metabolite levels ( 23823483) Post bronchodilator FEV1/FVC ratio ( 26634245) Pulse pressure ( 28739976 30487518) Serum metabolite levels (CMS) ( 31636271) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		65 interacting genes: A1CF ARHGEF5 ARMC7 BEX2 CCDC120 CCDC187 CDC42 CDKN2C CHIC2 COIL DCUN1D5 DPPA3 DTX2 DUSP13 FAM161A FGD2 GATA3 GCM2 GSTZ1 HCK HOXB9 HOXC8 KRT3 KRT75 MALSU1 MATR3 MDFI METAP1 MSRB3 MTA1 MYEF2 MYOZ1 NATD1 OTX1 PFKFB1 PKP2 PPP1R32 PRPF18 PRPF31 PSMB1 RHOA RIN1 SAXO1 SETD5 SH2D4A SHISA6 SIX1 SMCP SMG9 TBC1D22B TBX18 TEKT3 TENT5D TFAP2D TFG TRIM55 TRIM63 TSSK3 TTC23 USP2 VPS37C ZCCHC14 ZNF148 ZNF319 ZNF648	65 interacting genes: ADAMTSL4 AGXT AXIN2 C1QTNF2 CARD10 CATSPER1 CBY2 CDR2 CEP44 CYSRT1 DNAL4 FBLN1 GMCL1 HOXA1 ITSN2 KANK2 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP6-2 LCE1A LCE1C LCE1F LCE2C LCE3A LCE3C LCE3D LCE5A LCN2 LZTS2 MDFI MEOX2 MTUS2 MYF5 MYPOP NBPF19 NDUFB7 NOTCH2NLA OTX1 PLEKHF1 PLEKHF2 PLEKHG4 PNMA1 POU4F2 PPARA REL SCNM1 SDCBP TCF4 TOP3B TUBGCP4 U2AF2 ZNF330 ZNF837
Entrez ID		25894	26511
HPRD ID		10890	10373
Ensembl ID		ENSG00000196155	ENSG00000109220
Uniprot IDs		A0A024R6X4 Q58EX7	Q9UKJ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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