UNC93B1 and SLC16A2

Data Source:
BioGRID (two hybrid)

		UNC93B1	SLC16A2
Description		unc-93 homolog B1, TLR signaling regulator	solute carrier family 16 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosome Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Early Phagosome	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Apical Plasma Membrane
	Molecular Function	Protein Binding Toll-like Receptor Binding	Transporter Activity Monocarboxylic Acid Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity Symporter Activity Thyroid Hormone Transmembrane Transporter Activity
	Biological Process	Toll-like Receptor Signaling Pathway Adaptive Immune Response Intracellular Protein Transport Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 7 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Innate Immune Response Defense Response To Virus	Cellular Amino Acid Metabolic Process Monocarboxylic Acid Transport Thyroid Hormone Metabolic Process Sodium-independent Organic Anion Transport Thyroid Hormone Transport Amino Acid Import Across Plasma Membrane Transport Across Blood-brain Barrier Negative Regulation Of Neural Precursor Cell Proliferation
Pathways		Trafficking and processing of endosomal TLR UNC93B1 deficiency - HSE	Transport of organic anions
Drugs			Pyruvic acid
Diseases			Allan-Herndon-Dudley syndrome; Monocarboxylate transporter 8 deficiency
GWAS
Interacting Genes		27 interacting genes: BEST2 CCDC107 CD79A CLDN7 CLPTM1 CREB3L1 EBP ERGIC3 FATE1 FFAR3 GPR101 GPR37L1 GPRC5D HHLA2 KLRC1 LDLRAD1 LEUTX LIME1 MBOAT7 MFF REEP1 SLC16A2 SLC35C2 SSMEM1 SYNDIG1 TM4SF18 TMEM237	38 interacting genes: ADIPOQ ANKRD46 APOL3 BTN2A2 C3orf52 CCL2 CNIH3 COL4A5 CXCL16 CYB5B EFNA5 FAM3C JAGN1 LAT LEPROTL1 LHFPL5 LPAR3 MFSD6 MS4A13 PLP1 PNLIPRP1 SERPINA7 SLC30A2 SLC38A7 SLC39A13 SLC39A9 SMCO4 SYNGR1 THRA TMEM254 TMEM60 TOMM6 TRARG1 TSPO2 UNC93B1 UPK1B VAMP3 VEGFA
Entrez ID		81622	6567
HPRD ID		12191	02106
Ensembl ID		ENSG00000110057	ENSG00000147100
Uniprot IDs		Q9H1C4	P36021
PDB IDs
Enriched GO Terms of Interacting Partners?
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