UNC93B1 and REEP1

Data Source:
BioGRID (two hybrid)

		UNC93B1	REEP1
Description		unc-93 homolog B1, TLR signaling regulator	receptor accessory protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosome Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Early Phagosome	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytoplasmic Microtubule Membrane Integral Component Of Membrane Mitochondrial Membrane Endoplasmic Reticulum Tubular Network
	Molecular Function	Protein Binding Toll-like Receptor Binding	Protein Binding Microtubule Binding Olfactory Receptor Binding
	Biological Process	Toll-like Receptor Signaling Pathway Adaptive Immune Response Intracellular Protein Transport Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 7 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Innate Immune Response Defense Response To Virus	Protein Insertion Into Membrane Endoplasmic Reticulum Tubular Network Organization
Pathways		Trafficking and processing of endosomal TLR UNC93B1 deficiency - HSE	Olfactory Signaling Pathway
Drugs
Diseases			Hereditary spastic paraplegia (SPG)
GWAS			Atrial fibrillation ( 30061737 29892015) Facial emotion recognition (sad faces) ( 28608620) Night sleep phenotypes ( 27126917)
Interacting Genes		27 interacting genes: BEST2 CCDC107 CD79A CLDN7 CLPTM1 CREB3L1 EBP ERGIC3 FATE1 FFAR3 GPR101 GPR37L1 GPRC5D HHLA2 KLRC1 LDLRAD1 LEUTX LIME1 MBOAT7 MFF REEP1 SLC16A2 SLC35C2 SSMEM1 SYNDIG1 TM4SF18 TMEM237	7 interacting genes: CLDN10 CSRP1 STX7 TMEM100 TMEM42 TMEM97 UNC93B1
Entrez ID		81622	65055
HPRD ID		12191	07810
Ensembl ID		ENSG00000110057	ENSG00000068615
Uniprot IDs		Q9H1C4	Q9H902
PDB IDs
Enriched GO Terms of Interacting Partners?
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