MED28 and MED8

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vitro)

		MED28	MED8
Description		mediator complex subunit 28	mediator complex subunit 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Membrane Mediator Complex Cortical Actin Cytoskeleton	Nucleoplasm Mediator Complex Core Mediator Complex
	Molecular Function	Actin Binding Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Coregulator Activity Protein Binding
	Biological Process	Stem Cell Population Maintenance Negative Regulation Of Smooth Muscle Cell Differentiation	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Protein Ubiquitination
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS			Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Feeling worry ( 29500382) Schizophrenia ( 28991256) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		17 interacting genes: CBY2 FYN GRB2 KLHL12 LCK MAGEA11 MED30 MED8 MED9 MIIP NF2 PRMT6 PUF60 SRC SUOX TCP11 USHBP1	32 interacting genes: APP ARRB2 CCNC CDK8 CTDP1 ELOC HSPB3 KRT40 MED1 MED11 MED12 MED17 MED19 MED20 MED22 MED25 MED26 MED27 MED28 MED30 MED31 MED6 MED7 MED9 PEX14 PHYHIP PNMA1 PRKAR1B SNTA1 THOC7 UBALD1 USP49
Entrez ID		80306	112950
HPRD ID		14381	06991
Ensembl ID		ENSG00000118579	ENSG00000159479
Uniprot IDs		Q9H204	Q96G25
PDB IDs
Enriched GO Terms of Interacting Partners?
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