MED28 and PUF60

Data Source:
BioGRID (two hybrid, two hybrid)

		MED28	PUF60
Description		mediator complex subunit 28	poly(U) binding splicing factor 60
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Membrane Mediator Complex Cortical Actin Cytoskeleton	Nucleoplasm Cell Junction
	Molecular Function	Actin Binding Protein Binding	DNA Binding RNA Binding Protein Binding Identical Protein Binding Cadherin Binding
	Biological Process	Stem Cell Population Maintenance Negative Regulation Of Smooth Muscle Cell Differentiation	Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Splice Site Selection Apoptotic Process
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Interacting Genes		17 interacting genes: CBY2 FYN GRB2 KLHL12 LCK MAGEA11 MED30 MED8 MED9 MIIP NF2 PRMT6 PUF60 SRC SUOX TCP11 USHBP1	101 interacting genes: ARL8A BORCS5 CACNA1A CCNC CD101 CHD3 CPEB2 DDIT4L ERG FBXO7 FHL2 FTHL17 FUBP1 H1-2 ID3 IQCN KHDC4 MED28 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR9-1 MIR9-3 MIR92A1 MIR92A2 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F2 MIRLET7G MIRLET7I PCBP1 PCBP3 PPP1R16A PTBP2 QRICH1 RAD23B RAP1GDS1 SAP30BP SDCBP SF1 SIAH1 SNRPF SRSF11 TAF2 TH U2AF2 UBE2I UBTFL1 UPF2 VIM YWHAG ZG16
Entrez ID		80306	22827
HPRD ID		14381	18051
Ensembl ID		ENSG00000118579	ENSG00000179950
Uniprot IDs		Q9H204	Q9UHX1
PDB IDs			2DNY 2KXF 2KXH 2QFJ 3DXB 3UE2 3US5 3UWT 5KVY 5KW1 5KW6 5KWQ 6LUR 6SLO
Enriched GO Terms of Interacting Partners?
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