MED28 and MED30

Data Source:
BioGRID (affinity chromatography technology, two hybrid, affinity chromatography technology)
HPRD (two hybrid, in vivo, in vitro)

		MED28	MED30
Description		mediator complex subunit 28	mediator complex subunit 30
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Membrane Mediator Complex Cortical Actin Cytoskeleton	Ubiquitin Ligase Complex Nucleus Nucleoplasm Mediator Complex
	Molecular Function	Actin Binding Protein Binding	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Nuclear Receptor Coactivator Activity Vitamin D Receptor Binding Thyroid Hormone Receptor Binding Ubiquitin Protein Ligase Activity
	Biological Process	Stem Cell Population Maintenance Negative Regulation Of Smooth Muscle Cell Differentiation	Transcription Initiation From RNA Polymerase II Promoter Protein Ubiquitination Stem Cell Population Maintenance Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS			Common carotid intima-media thickness ( 29206233) Common carotid intima-media thickness in HIV infection ( 29206233) Dimensional psychopathology (Arousal) ( 29496196) Facial attractiveness (female raters) ( 30946739) Fasting blood glucose ( 29212154) Kawasaki disease ( 22446961) Leprosy ( 27976721) Midgestational total 25-hydroxyvitamin D levels (fetal genetic effect) ( 32047095) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Urate levels in obese individuals ( 25811787) Vestibular neuritis ( 30079052)
Interacting Genes		17 interacting genes: CBY2 FYN GRB2 KLHL12 LCK MAGEA11 MED30 MED8 MED9 MIIP NF2 PRMT6 PUF60 SRC SUOX TCP11 USHBP1	17 interacting genes: APP DOCK8 HGS IFT20 KRTAP10-9 MED17 MED22 MED27 MED28 MED4 MED8 MED9 MTA2 NAP1L2 NME7 PCBD2 SS18L1
Entrez ID		80306	90390
HPRD ID		14381	11631
Ensembl ID		ENSG00000118579	ENSG00000164758
Uniprot IDs		Q9H204	Q96HR3
PDB IDs
Enriched GO Terms of Interacting Partners?
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