CCDC6 and LRSAM1

Data Source:
BioGRID (two hybrid)

		CCDC6	LRSAM1
Description		coiled-coil domain containing 6	leucine rich repeat and sterile alpha motif containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton	Cytoplasm Cytosol Membrane
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding SH3 Domain Binding Identical Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Cytoskeleton Organization Biological_process	Protein Polyubiquitination Autophagy Protein Catabolic Process Negative Regulation Of Endocytosis Viral Budding Protein Autoubiquitination Ubiquitin-dependent Endocytosis Positive Regulation Of Xenophagy Positive Regulation Of Autophagosome Assembly
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases		Thyroid cancer
GWAS		Alopecia areata ( 25608926) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483) Monocyte percentage of white cells ( 32888494) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)	Mean corpuscular volume ( 32888494)
Interacting Genes		32 interacting genes: ATF2 ATF5 CCDC136 CCDC33 CENPQ CREB1 CSNK2A1 CYTH4 FBXW7 GAS8 LHX3 LRSAM1 LUZP4 MAPK3 MAPK7 MEOX2 MTUS2 PAX6 PIN1 PPP4C SH3RF1 SNAPC1 SORBS3 TFIP11 TRIM14 UBE2I WAC ZNF250 ZNF354C ZNF620 ZNF774 ZNF835	42 interacting genes: ATXN1 ATXN7 CCDC6 DMAP1 FAM178B GABARAPL2 GPR108 GRIK5 GSK3A KLC1 MAGEA1 MDM4 MGAT4B MKRN3 MUTYH MYL2 NINL PHF23 RNF111 RXRG TERF1 TNFRSF10C TRIM17 TRIM74 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2H UBE2I UBE2J1 UBE2K UBE2N UBE2W UEVLD USP2 USP21 VPS11 XAF1 ZMAT4
Entrez ID		8030	90678
HPRD ID		09064	14325
Ensembl ID		ENSG00000108091	ENSG00000148356
Uniprot IDs		Q05CP8 Q16204	A0A024R870 Q6UWE0
PDB IDs
Enriched GO Terms of Interacting Partners?
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