CENPT and DHX29

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CENPT	DHX29
Description		centromere protein T	DExH-box helicase 29
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Condensed Nuclear Chromosome Kinetochore Nucleoplasm Cytosol Nuclear Body	Intracellular Anatomical Structure Eukaryotic 43S Preinitiation Complex Cytosolic Small Ribosomal Subunit
	Molecular Function	DNA Binding Protein Binding Protein Heterodimerization Activity	RNA Binding RNA Helicase Activity Translation Initiation Factor Activity ATP Binding Translation Activator Activity Nucleoside-triphosphatase Activity Ribosomal Small Subunit Binding Cadherin Binding
	Biological Process	Mitotic Cell Cycle Chromosome Segregation CENP-A Containing Nucleosome Assembly Chromosome Organization Cell Division Kinetochore Assembly Protein Localization To Kinetochore Involved In Kinetochore Assembly	Formation Of Translation Preinitiation Complex Ribosome Assembly Positive Regulation Of Translational Initiation
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Cocaine dependence ( 31212010)
Interacting Genes		8 interacting genes: APP CENPW COPS5 DHX29 H3C1 PPCDC SNCB TCEA2	3 interacting genes: CENPT PISD TBC1D17
Entrez ID		80152	54505
HPRD ID		07811	10882
Ensembl ID		ENSG00000102901	ENSG00000067248
Uniprot IDs		B3KPB2 Q96BT3	Q7Z478
PDB IDs
Enriched GO Terms of Interacting Partners?
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