ZNF212 and DUSP6

Data Source:
BioGRID (two hybrid)

		ZNF212	DUSP6
Description		zinc finger protein 212	dual specificity phosphatase 6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/threonine Phosphatase Activity MAP Kinase Tyrosine/serine/threonine Phosphatase Activity Mitogen-activated Protein Kinase Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II	MAPK Cascade Activation Of MAPK Activity Inactivation Of MAPK Activity Protein Dephosphorylation Response To Organic Cyclic Compound Cell Differentiation Peptidyl-tyrosine Dephosphorylation Peptidyl-threonine Dephosphorylation Response To Drug Positive Regulation Of Apoptotic Process Response To Nitrosative Stress Regulation Of Heart Growth Negative Regulation Of ERK1 And ERK2 Cascade Response To Growth Factor
Pathways		Generic Transcription Pathway	RAF-independent MAPK1/3 activation ERKs are inactivated Negative regulation of MAPK pathway Signaling by MAPK mutants
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Attention deficit hyperactivity disorder ( 29325848 30478444) Night sleep phenotypes ( 27126917)
Interacting Genes		30 interacting genes: - ATF3 ATF4 BYSL CREB3L2 CSK DPF2 DUSP6 FAM90A1 FHL2 GAS8 GNL1 GYS1 HBP1 KANK2 MLH1 NFKBIA NKX2-3 PPARGC1B PRKAA2 PTP4A1 RND1 SAP30BP SF3A3 SUV39H2 ZNF3 ZNF331 ZNF408 ZNF783 ZZZ3	12 interacting genes: AATK ERBB4 LMTK2 LTK MAPK1 MAPK3 MDFI ROR2 SRPK1 TEX11 TXK ZNF212
Entrez ID		7988	1848
HPRD ID		03859	04124
Ensembl ID		ENSG00000170260	ENSG00000139318
Uniprot IDs		A0A090N8N3 B3KQE6 Q9UDV6	A0A024RBC1 Q16828 Q53GP9
PDB IDs			1HZM 1MKP
Enriched GO Terms of Interacting Partners?
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