ZNF212 and NKX2-3

Data Source:
BioGRID (two hybrid)

		ZNF212	NKX2-3
Description		zinc finger protein 212	NK2 homeobox 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Chromatin Cellular_component Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II	Leukocyte Homeostasis Plasma Cell Differentiation Regulation Of Transcription By RNA Polymerase II Triglyceride Metabolic Process Biological_process Gland Morphogenesis Cell Differentiation Macrophage Differentiation Regulation Of Cell Population Proliferation Odontogenesis Of Dentin-containing Tooth CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Lymph Node Development Spleen Development Peyer's Patch Development Post-embryonic Digestive Tract Morphogenesis Leukocyte Migration
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Ankylosing spondylitis ( 23749187) Autoimmune thyroid disease ( 32581359) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Colorectal cancer ( 25990418 30529582 24737748) Colorectal cancer or advanced adenoma ( 30510241) Crohn's disease ( 18587394 25489960 28067908 17554261 22412388 17554300 21102463) Dental caries ( 23064961) Granulocyte percentage of myeloid white cells ( 27863252) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Hypothyroidism ( 27182965) Inflammatory bowel disease ( 28067908 23128233) Leukocyte telomere length ( 31171785) Mean corpuscular hemoglobin ( 27863252) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) Pediatric autoimmune diseases ( 26301688) Red blood cell traits ( 23222517) Ulcerative colitis ( 28067908 20228798 20228799)
Interacting Genes		30 interacting genes: - ATF3 ATF4 BYSL CREB3L2 CSK DPF2 DUSP6 FAM90A1 FHL2 GAS8 GNL1 GYS1 HBP1 KANK2 MLH1 NFKBIA NKX2-3 PPARGC1B PRKAA2 PTP4A1 RND1 SAP30BP SF3A3 SUV39H2 ZNF3 ZNF331 ZNF408 ZNF783 ZZZ3	3 interacting genes: GTF2A1L SRF ZNF212
Entrez ID		7988	159296
HPRD ID		03859	05992
Ensembl ID		ENSG00000170260	ENSG00000119919
Uniprot IDs		A0A090N8N3 B3KQE6 Q9UDV6	Q8TAU0
PDB IDs
Enriched GO Terms of Interacting Partners?
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