CENPU and MLF1

Data Source:
HPRD (two hybrid, in vitro)

		CENPU	MLF1
Description		centromere protein U	myeloid leukemia factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Kinetochore Nucleus Nucleoplasm Cytosol Centriolar Satellite	Nucleus Cytoplasm Cilium Ciliary Basal Body
	Molecular Function	Protein Binding	DNA Binding Protein Binding Protein Domain Specific Binding
	Biological Process	Viral Process CENP-A Containing Nucleosome Assembly Chordate Embryonic Development	Myeloid Progenitor Cell Differentiation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle Arrest
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Depression ( 29700475) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Major depressive disorder ( 27479909) PR interval ( 32439900) Sporadic neuroblastoma ( 28545128) Systolic blood pressure ( 30224653)
Interacting Genes		17 interacting genes: E2F6 EIF4G1 GIT1 LAMC1 MLF1 NDUFS2 NUP62 PGRMC1 PLK2 PLK3 PLXNB2 ROBO2 SPTBN4 TFIP11 TUBB2B UPF2 XRCC6	9 interacting genes: CENPU COP1 COPS3 DNAJB6 GRIK5 MAGEA11 MEOX2 NRBP1 YWHAZ
Entrez ID		79682	4291
HPRD ID		14722	03239
Ensembl ID		ENSG00000151725	ENSG00000178053
Uniprot IDs		Q71F23	A0A0S2Z4U8 A0A140VKD2 B2RD48 P58340 Q2TLE4 Q5HYH4
PDB IDs			3UAL 3UBW
Enriched GO Terms of Interacting Partners?
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