Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
CENPU and PLK3
Data Source:
BioGRID
(unspecified method)
CENPU
PLK3
Description
centromere protein U
polo like kinase 3
Image
No pdb structure
GO Annotations
Cellular Component
Condensed Chromosome Kinetochore
Nucleus
Nucleoplasm
Cytosol
Centriolar Satellite
Spindle Pole
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Golgi Stack
Centrosome
Dendrite
Neuronal Cell Body
Molecular Function
Protein Binding
P53 Binding
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Biological Process
Viral Process
CENP-A Containing Nucleosome Assembly
Chordate Embryonic Development
G1/S Transition Of Mitotic Cell Cycle
G2/M Transition Of Mitotic Cell Cycle
Negative Regulation Of Transcription By RNA Polymerase II
Mitotic Cell Cycle
Response To Reactive Oxygen Species
Protein Phosphorylation
Apoptotic Process
Response To Osmotic Stress
Cellular Response To DNA Damage Stimulus
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Mitotic Cell Cycle Checkpoint
Endomitotic Cell Cycle
Response To Radiation
Cytoplasmic Microtubule Organization
Regulation Of Cytokinesis
Negative Regulation Of Apoptotic Process
Protein Kinase B Signaling
Mitotic G1/S Transition Checkpoint
Regulation Of Cell Division
Golgi Disassembly
Positive Regulation Of Intracellular Protein Transport
Regulation Of Signal Transduction By P53 Class Mediator
Positive Regulation Of Chaperone-mediated Autophagy
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Involved In Cellular Response To Hypoxia
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Deposition of new CENPA-containing nucleosomes at the centromere
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Regulation of TP53 Activity through Phosphorylation
Drugs
Fostamatinib
Diseases
GWAS
Interacting Genes
17 interacting genes:
E2F6
EIF4G1
GIT1
LAMC1
MLF1
NDUFS2
NUP62
PGRMC1
PLK2
PLK3
PLXNB2
ROBO2
SPTBN4
TFIP11
TUBB2B
UPF2
XRCC6
24 interacting genes:
AURKA
BCL2L1
CDC25C
CENPU
CHEK2
CIB1
HIF1A
LSM5
MAP2K1
MAPK1
MFF
PLK1
POU2F1
PPM1A
RAD52
RNF141
RRM2
SLX4
SNCA
SNCB
TNS2
TP53
TRIP13
VRK1
Entrez ID
79682
1263
HPRD ID
14722
04222
Ensembl ID
ENSG00000151725
ENSG00000173846
Uniprot IDs
Q71F23
Q9H4B4
PDB IDs
4B6L
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?