MLF1 and CENPU

Data Source:
HPRD (two hybrid, in vitro)

		MLF1	CENPU
Description		myeloid leukemia factor 1	centromere protein U
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cilium Ciliary Basal Body	Condensed Chromosome Kinetochore Nucleus Nucleoplasm Cytosol Centriolar Satellite
	Molecular Function	DNA Binding Protein Binding Protein Domain Specific Binding	Protein Binding
	Biological Process	Myeloid Progenitor Cell Differentiation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle Arrest	Viral Process CENP-A Containing Nucleosome Assembly Chordate Embryonic Development
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Depression ( 29700475) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Major depressive disorder ( 27479909) PR interval ( 32439900) Sporadic neuroblastoma ( 28545128) Systolic blood pressure ( 30224653)
Interacting Genes		9 interacting genes: CENPU COP1 COPS3 DNAJB6 GRIK5 MAGEA11 MEOX2 NRBP1 YWHAZ	17 interacting genes: E2F6 EIF4G1 GIT1 LAMC1 MLF1 NDUFS2 NUP62 PGRMC1 PLK2 PLK3 PLXNB2 ROBO2 SPTBN4 TFIP11 TUBB2B UPF2 XRCC6
Entrez ID		4291	79682
HPRD ID		03239	14722
Ensembl ID		ENSG00000178053	ENSG00000151725
Uniprot IDs		A0A0S2Z4U8 A0A140VKD2 B2RD48 P58340 Q2TLE4 Q5HYH4	Q71F23
PDB IDs		3UAL 3UBW
Enriched GO Terms of Interacting Partners?
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