PHF23 and LRSAM1

Data Source:
BioGRID (affinity chromatography technology, pull down)
HPRD (two hybrid)

		PHF23	LRSAM1
Description		PHD finger protein 23	leucine rich repeat and sterile alpha motif containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Cytoplasm Cytosol Membrane
	Molecular Function	Protein Binding Metal Ion Binding	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Autophagy Positive Regulation Of Protein Ubiquitination Negative Regulation Of Autophagosome Maturation Negative Regulation Of Autophagosome Assembly	Protein Polyubiquitination Autophagy Protein Catabolic Process Negative Regulation Of Endocytosis Viral Budding Protein Autoubiquitination Ubiquitin-dependent Endocytosis Positive Regulation Of Xenophagy Positive Regulation Of Autophagosome Assembly
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494)	Mean corpuscular volume ( 32888494)
Interacting Genes		6 interacting genes: ERBB2 LRSAM1 PRSS23 STK11 TRIM55 TRIM63	42 interacting genes: ATXN1 ATXN7 CCDC6 DMAP1 FAM178B GABARAPL2 GPR108 GRIK5 GSK3A KLC1 MAGEA1 MDM4 MGAT4B MKRN3 MUTYH MYL2 NINL PHF23 RNF111 RXRG TERF1 TNFRSF10C TRIM17 TRIM74 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2H UBE2I UBE2J1 UBE2K UBE2N UBE2W UEVLD USP2 USP21 VPS11 XAF1 ZMAT4
Entrez ID		79142	90678
HPRD ID		08325	14325
Ensembl ID		ENSG00000040633	ENSG00000148356
Uniprot IDs		Q9BUL5	A0A024R870 Q6UWE0
PDB IDs		6WXK
Enriched GO Terms of Interacting Partners?
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