DUSP26 and PTK7

Data Source:
BioGRID (two hybrid)

		DUSP26	PTK7
Description		dual specificity phosphatase 26	protein tyrosine kinase 7 (inactive)
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion
	Molecular Function	RNA Polymerase II Activating Transcription Factor Binding P53 Binding Phosphoserine Phosphatase Activity Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Protein Kinase Activity Protein Binding ATP Binding Cell Adhesion Molecule Binding Coreceptor Activity Involved In Wnt Signaling Pathway, Planar Cell Polarity Pathway
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Positive Regulation Of Cell Adhesion Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Peptidyl-serine Dephosphorylation	Establishment Of Planar Polarity Kidney Development Ventricular Septum Development Axis Elongation Protein Phosphorylation Cell Adhesion Signal Transduction Positive Regulation Of Neuron Projection Development Cell Migration Actin Cytoskeleton Reorganization Wound Healing Establishment Of Epithelial Cell Apical/basal Polarity Convergent Extension Lung-associated Mesenchyme Development Regulation Of Canonical Wnt Signaling Pathway Coronary Vasculature Development Cellular Response To Retinoic Acid Cochlea Morphogenesis Planar Cell Polarity Pathway Involved In Neural Tube Closure Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Body mass index ( 28892062 25673413) Chronotype ( 30696823) General risk tolerance (MTAG) ( 30643258) Metabolite levels ( 23823483) Morning person ( 30696823) Reading disability ( 32108986) Self-reported risk-taking behaviour ( 30271922)	Coronary artery disease ( 29212778)
Interacting Genes		11 interacting genes: CALCOCO2 CARD10 EPHA2 EPHA7 GOLGA6L9 GRIPAP1 HSF4 IGF1R KRT27 PTK7 RET	38 interacting genes: CDC14A CLNK CTDSP2 DUSP10 DUSP14 DUSP15 DUSP18 DUSP19 DUSP21 DUSP26 DUSP29 ERBB2 ILKAP KRTAP1-3 KRTAP10-8 MDFI MTMR1 MTMR10 MTMR6 MTMR9 MTUS2 NBPF19 NOTCH2NLA PPM1A PPM1B PPM1F PPM1K PPP3CA PPP3CB PTEN PTPN11 PTPN12 PTPN6 PTPN7 PTPRR STYX TPTE TPTE2
Entrez ID		78986	5754
HPRD ID		14421	03534
Ensembl ID		ENSG00000133878	ENSG00000112655
Uniprot IDs		Q9BV47	Q13308
PDB IDs		2E0T 4B04 4HRF 5GTJ	6VG3
Enriched GO Terms of Interacting Partners?
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