PTK7 and STYX

Data Source:
BioGRID (two hybrid)

		PTK7	STYX
Description		protein tyrosine kinase 7 (inactive)	serine/threonine/tyrosine interacting protein
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding Cell Adhesion Molecule Binding Coreceptor Activity Involved In Wnt Signaling Pathway, Planar Cell Polarity Pathway	Pseudophosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity F-box Domain Binding
	Biological Process	Establishment Of Planar Polarity Kidney Development Ventricular Septum Development Axis Elongation Protein Phosphorylation Cell Adhesion Signal Transduction Positive Regulation Of Neuron Projection Development Cell Migration Actin Cytoskeleton Reorganization Wound Healing Establishment Of Epithelial Cell Apical/basal Polarity Convergent Extension Lung-associated Mesenchyme Development Regulation Of Canonical Wnt Signaling Pathway Coronary Vasculature Development Cellular Response To Retinoic Acid Cochlea Morphogenesis Planar Cell Polarity Pathway Involved In Neural Tube Closure Positive Regulation Of Canonical Wnt Signaling Pathway	Protein Dephosphorylation Negative Regulation Of Protein Binding Negative Regulation Of Catalytic Activity MAPK Export From Nucleus Negative Regulation Of SCF-dependent Proteasomal Ubiquitin-dependent Catabolic Process Regulation Of ERK1 And ERK2 Cascade
Pathways
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778)	Prostate cancer ( 23535732)
Interacting Genes		38 interacting genes: CDC14A CLNK CTDSP2 DUSP10 DUSP14 DUSP15 DUSP18 DUSP19 DUSP21 DUSP26 DUSP29 ERBB2 ILKAP KRTAP1-3 KRTAP10-8 MDFI MTMR1 MTMR10 MTMR6 MTMR9 MTUS2 NBPF19 NOTCH2NLA PPM1A PPM1B PPM1F PPM1K PPP3CA PPP3CB PTEN PTPN11 PTPN12 PTPN6 PTPN7 PTPRR STYX TPTE TPTE2	24 interacting genes: AATK CARHSP1 EGFR EPHA2 EPHA3 EPHA7 EPHB6 ERBB2 ERBB3 ERBB4 FBXO7 FBXW7 IGF1R INSR INSRR KDR KIT LMTK2 MAPK1 MUSK PTK7 ROR1 ROR2 TEK
Entrez ID		5754	6815
HPRD ID		03534	10258
Ensembl ID		ENSG00000112655	ENSG00000198252
Uniprot IDs		Q13308	A0A024R641 Q8WUJ0
PDB IDs		6VG3	2R0B
Enriched GO Terms of Interacting Partners?
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