PTK7 and DUSP26

Data Source:
BioGRID (two hybrid)

		PTK7	DUSP26
Description		protein tyrosine kinase 7 (inactive)	dual specificity phosphatase 26
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Extracellular Exosome
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding Cell Adhesion Molecule Binding Coreceptor Activity Involved In Wnt Signaling Pathway, Planar Cell Polarity Pathway	RNA Polymerase II Activating Transcription Factor Binding P53 Binding Phosphoserine Phosphatase Activity Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Establishment Of Planar Polarity Kidney Development Ventricular Septum Development Axis Elongation Protein Phosphorylation Cell Adhesion Signal Transduction Positive Regulation Of Neuron Projection Development Cell Migration Actin Cytoskeleton Reorganization Wound Healing Establishment Of Epithelial Cell Apical/basal Polarity Convergent Extension Lung-associated Mesenchyme Development Regulation Of Canonical Wnt Signaling Pathway Coronary Vasculature Development Cellular Response To Retinoic Acid Cochlea Morphogenesis Planar Cell Polarity Pathway Involved In Neural Tube Closure Positive Regulation Of Canonical Wnt Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Positive Regulation Of Cell Adhesion Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Peptidyl-serine Dephosphorylation
Pathways
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778)	Body mass index ( 28892062 25673413) Chronotype ( 30696823) General risk tolerance (MTAG) ( 30643258) Metabolite levels ( 23823483) Morning person ( 30696823) Reading disability ( 32108986) Self-reported risk-taking behaviour ( 30271922)
Interacting Genes		38 interacting genes: CDC14A CLNK CTDSP2 DUSP10 DUSP14 DUSP15 DUSP18 DUSP19 DUSP21 DUSP26 DUSP29 ERBB2 ILKAP KRTAP1-3 KRTAP10-8 MDFI MTMR1 MTMR10 MTMR6 MTMR9 MTUS2 NBPF19 NOTCH2NLA PPM1A PPM1B PPM1F PPM1K PPP3CA PPP3CB PTEN PTPN11 PTPN12 PTPN6 PTPN7 PTPRR STYX TPTE TPTE2	11 interacting genes: CALCOCO2 CARD10 EPHA2 EPHA7 GOLGA6L9 GRIPAP1 HSF4 IGF1R KRT27 PTK7 RET
Entrez ID		5754	78986
HPRD ID		03534	14421
Ensembl ID		ENSG00000112655	ENSG00000133878
Uniprot IDs		Q13308	Q9BV47
PDB IDs		6VG3	2E0T 4B04 4HRF 5GTJ
Enriched GO Terms of Interacting Partners?
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