CA3 and LXN

Data Source:
BioGRID (two hybrid)

		CA3	LXN
Description		carbonic anhydrase 3	latexin
Image
GO Annotations	Cellular Component	Cytosol	Extracellular Space Cytoplasm
	Molecular Function	Carbonate Dehydratase Activity Protein Binding Zinc Ion Binding Nickel Cation Binding Phosphatase Activity Hydro-lyase Activity	Protein Binding Metalloendopeptidase Inhibitor Activity Heparin Binding
	Biological Process	One-carbon Metabolic Process Response To Oxidative Stress Response To Bacterium Bicarbonate Transport Dephosphorylation Response To Ethanol	Inflammatory Response Negative Regulation Of Endopeptidase Activity Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain
Pathways		Reversible hydration of carbon dioxide
Drugs		Topiramate Ethoxzolamide Sulpiride Celecoxib Benzthiazide Valdecoxib Cyclothiazide Methazolamide Acetazolamide Dorzolamide Zonisamide Diclofenamide Brinzolamide Ellagic acid Saccharin
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Blood trace element (Zn levels) ( 23720494) Estimated glomerular filtration rate ( 31152163) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin concentration ( 27863252)	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143)
Interacting Genes		3 interacting genes: HPCAL1 LXN SRC	25 interacting genes: BOC CA3 COX6A1 CYBC1 DNAJC11 DPYD FCGR3A GSG1L IGSF11 MAGEA8 MCMDC2 NSMF PAX6 PPP1R3C RNF4 SHKBP1 SPAG7 TMEM14A TRAIP TRIM39 YIF1B ZCCHC17 ZKSCAN4 ZNF430 ZNF679
Entrez ID		761	56925
HPRD ID		00260	14327
Ensembl ID		ENSG00000164879	ENSG00000079257
Uniprot IDs		P07451 V9HWA3	Q9BS40
PDB IDs		1Z93 1Z97 2HFW 3UYN 3UYQ	2BO9
Enriched GO Terms of Interacting Partners?
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