LXN and SHKBP1

		LXN	SHKBP1
Description		latexin	SH3KBP1 binding protein 1
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GO Annotations	Cellular Component	Extracellular Space Cytoplasm	Lysosome
	Molecular Function	Protein Binding Metalloendopeptidase Inhibitor Activity Heparin Binding	Protein Binding Identical Protein Binding
	Biological Process	Inflammatory Response Negative Regulation Of Endopeptidase Activity Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain	Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143)	Carotid intima media thickness (mean) ( 31801372) Cleft lip with or without cleft palate x maternal periconceptional smoking interaction (parent of origin effect) ( 31372216) Hemoglobin levels ( 32327693)
Interacting Genes		25 interacting genes: BOC CA3 COX6A1 CYBC1 DNAJC11 DPYD FCGR3A GSG1L IGSF11 MAGEA8 MCMDC2 NSMF PAX6 PPP1R3C RNF4 SHKBP1 SPAG7 TMEM14A TRAIP TRIM39 YIF1B ZCCHC17 ZKSCAN4 ZNF430 ZNF679	10 interacting genes: CCNG1 COL7A1 CUL3 GRB2 LXN NR3C1 PIN1 PRPF3 SH3KBP1 YWHAG
Entrez ID		56925	92799
HPRD ID		14327	15338
Ensembl ID		ENSG00000079257	ENSG00000160410
Uniprot IDs		Q9BS40	B3KVX8 Q8TBC3
PDB IDs		2BO9	4CRH
Enriched GO Terms of Interacting Partners?
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