LXN and CA3

Data Source:
BioGRID (two hybrid)

		LXN	CA3
Description		latexin	carbonic anhydrase 3
Image
GO Annotations	Cellular Component	Extracellular Space Cytoplasm	Cytosol
	Molecular Function	Protein Binding Metalloendopeptidase Inhibitor Activity Heparin Binding	Carbonate Dehydratase Activity Protein Binding Zinc Ion Binding Nickel Cation Binding Phosphatase Activity Hydro-lyase Activity
	Biological Process	Inflammatory Response Negative Regulation Of Endopeptidase Activity Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain	One-carbon Metabolic Process Response To Oxidative Stress Response To Bacterium Bicarbonate Transport Dephosphorylation Response To Ethanol
Pathways			Reversible hydration of carbon dioxide
Drugs			Topiramate Ethoxzolamide Sulpiride Celecoxib Benzthiazide Valdecoxib Cyclothiazide Methazolamide Acetazolamide Dorzolamide Zonisamide Diclofenamide Brinzolamide Ellagic acid Saccharin
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143)	Blood protein levels ( 30072576 29875488 28240269) Blood trace element (Zn levels) ( 23720494) Estimated glomerular filtration rate ( 31152163) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin concentration ( 27863252)
Interacting Genes		25 interacting genes: BOC CA3 COX6A1 CYBC1 DNAJC11 DPYD FCGR3A GSG1L IGSF11 MAGEA8 MCMDC2 NSMF PAX6 PPP1R3C RNF4 SHKBP1 SPAG7 TMEM14A TRAIP TRIM39 YIF1B ZCCHC17 ZKSCAN4 ZNF430 ZNF679	3 interacting genes: HPCAL1 LXN SRC
Entrez ID		56925	761
HPRD ID		14327	00260
Ensembl ID		ENSG00000079257	ENSG00000164879
Uniprot IDs		Q9BS40	P07451 V9HWA3
PDB IDs		2BO9	1Z93 1Z97 2HFW 3UYN 3UYQ
Enriched GO Terms of Interacting Partners?
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