LXN and COX6A1

Data Source:
BioGRID (two hybrid)

		LXN	COX6A1
Description		latexin	cytochrome c oxidase subunit 6A1
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GO Annotations	Cellular Component	Extracellular Space Cytoplasm	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex IV Integral Component Of Membrane
	Molecular Function	Protein Binding Metalloendopeptidase Inhibitor Activity Heparin Binding	Cytochrome-c Oxidase Activity Protein Binding Enzyme Regulator Activity
	Biological Process	Inflammatory Response Negative Regulation Of Endopeptidase Activity Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain	Generation Of Precursor Metabolites And Energy Mitochondrial Electron Transport, Cytochrome C To Oxygen Regulation Of Catalytic Activity Proton Transmembrane Transport
Pathways			TP53 Regulates Metabolic Genes Respiratory electron transport
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143)	Bipolar disorder ( 31043756) Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)
Interacting Genes		25 interacting genes: BOC CA3 COX6A1 CYBC1 DNAJC11 DPYD FCGR3A GSG1L IGSF11 MAGEA8 MCMDC2 NSMF PAX6 PPP1R3C RNF4 SHKBP1 SPAG7 TMEM14A TRAIP TRIM39 YIF1B ZCCHC17 ZKSCAN4 ZNF430 ZNF679	2 interacting genes: GRB2 LXN
Entrez ID		56925	1337
HPRD ID		14327	03644
Ensembl ID		ENSG00000079257	ENSG00000111775
Uniprot IDs		Q9BS40	H6SG15 P12074
PDB IDs		2BO9	5Z62
Enriched GO Terms of Interacting Partners?
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