ZNF24 and APLP1

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		ZNF24	APLP1
Description		zinc finger protein 24	amyloid beta precursor like protein 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Basement Membrane Nucleoplasm Golgi Apparatus Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding	Protein Binding Heparin Binding Alpha-2A Adrenergic Receptor Binding Alpha-2B Adrenergic Receptor Binding Alpha-2C Adrenergic Receptor Binding Identical Protein Binding Transition Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Myelination Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Endocytosis Apoptotic Process Cell Adhesion Nervous System Development Animal Organ Morphogenesis Extracellular Matrix Organization Forebrain Development Cellular Response To Norepinephrine Stimulus Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Pathways
Drugs			Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS			Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		54 interacting genes: APLP1 CCDC130 CEP126 COPS6 CRMP1 DDX6 DZIP3 EEF1A1 EEF1G ERG28 FAM161A FANCA HAP1 HMGB1 KAT5 LMO1 LMO2 LRIF1 MAP1LC3C MID2 MZF1 NEK6 PPP1CC PRPF31 RBM48 SCAND1 SEC62 SETDB1 TCAF1 TP53 TRIM25 TRIM41 UBE2I UNC119 UTP14A ZBTB16 ZGPAT ZKSCAN4 ZKSCAN8 ZNF165 ZNF174 ZNF232 ZNF396 ZNF410 ZNF444 ZNF446 ZNF620 ZNHIT3 ZSCAN12 ZSCAN16 ZSCAN21 ZSCAN22 ZSCAN23 ZSCAN32	43 interacting genes: ANXA7 APBB1 CDK4 CDKN1A CDKN2C CRCT1 CSNK2B DAB1 DAB2 EEF1A1 EIF2S2 ERBB2 GDF9 GSTM4 HAP1 HLA-DQA1 HSPE1 ING5 KAT5 LRIF1 MPHOSPH6 NACA PCDHA4 PHF10 PIN1 PNP PRNP RAP1B RBM48 RCC1 SAT1 SETDB1 SMN1 SNCA STX5 TCF21 TK1 TMSB4X TOE1 TSC22D1 UTP14A VIM ZNF24
Entrez ID		7572	333
HPRD ID		01921	00102
Ensembl ID		ENSG00000172466	ENSG00000105290
Uniprot IDs		P17028	P51693
PDB IDs		1X6E 3LHR	3PMR 3Q7G 3Q7L 3QMK 4RD9 4RDA
Enriched GO Terms of Interacting Partners?
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