APLP1 and NACA

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		APLP1	NACA
Description		amyloid beta precursor like protein 1	nascent polypeptide associated complex subunit alpha
Image
GO Annotations	Cellular Component	Basement Membrane Nucleoplasm Golgi Apparatus Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Nascent Polypeptide-associated Complex
	Molecular Function	Protein Binding Heparin Binding Alpha-2A Adrenergic Receptor Binding Alpha-2B Adrenergic Receptor Binding Alpha-2C Adrenergic Receptor Binding Identical Protein Binding Transition Metal Ion Binding	DNA Binding Unfolded Protein Binding
	Biological Process	Endocytosis Apoptotic Process Cell Adhesion Nervous System Development Animal Organ Morphogenesis Extracellular Matrix Organization Forebrain Development Cellular Response To Norepinephrine Stimulus Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway	Protein Targeting To Membrane
Pathways
Drugs		Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Severe influenza A (H1N1) infection ( 26379185)	Asthma ( 31619474) Atrial fibrillation ( 30061737 29892015) Diastolic blood pressure ( 30224653) JT interval ( 29874175) QRS duration ( 30012220)
Interacting Genes		43 interacting genes: ANXA7 APBB1 CDK4 CDKN1A CDKN2C CRCT1 CSNK2B DAB1 DAB2 EEF1A1 EIF2S2 ERBB2 GDF9 GSTM4 HAP1 HLA-DQA1 HSPE1 ING5 KAT5 LRIF1 MPHOSPH6 NACA PCDHA4 PHF10 PIN1 PNP PRNP RAP1B RBM48 RCC1 SAT1 SETDB1 SMN1 SNCA STX5 TCF21 TK1 TMSB4X TOE1 TSC22D1 UTP14A VIM ZNF24	17 interacting genes: APLP1 CCDC90B FADD FOS FUNDC2 IGSF21 JUN LRIF1 MDM2 PPP1R18 PTEN SMYD1 SPP1 TBP TXLNA UCHL5 ZHX1
Entrez ID		333	4666
HPRD ID		00102	03137
Ensembl ID		ENSG00000105290	ENSG00000196531
Uniprot IDs		P51693	A0A024RB41 Q13765
PDB IDs		3PMR 3Q7G 3Q7L 3QMK 4RD9 4RDA	3LKX 3MCB 3MCE
Enriched GO Terms of Interacting Partners?
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