APLP1 and PHF10

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		APLP1	PHF10
Description		amyloid beta precursor like protein 1	PHD finger protein 10
Image			No pdb structure
GO Annotations	Cellular Component	Basement Membrane Nucleoplasm Golgi Apparatus Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Nucleoplasm NpBAF Complex
	Molecular Function	Protein Binding Heparin Binding Alpha-2A Adrenergic Receptor Binding Alpha-2B Adrenergic Receptor Binding Alpha-2C Adrenergic Receptor Binding Identical Protein Binding Transition Metal Ion Binding	Transcription Coregulator Activity Histone Binding Metal Ion Binding
	Biological Process	Endocytosis Apoptotic Process Cell Adhesion Nervous System Development Animal Organ Morphogenesis Extracellular Matrix Organization Forebrain Development Cellular Response To Norepinephrine Stimulus Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway	Nervous System Development Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs		Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Severe influenza A (H1N1) infection ( 26379185)	Type 1 diabetes ( 21980299)
Interacting Genes		43 interacting genes: ANXA7 APBB1 CDK4 CDKN1A CDKN2C CRCT1 CSNK2B DAB1 DAB2 EEF1A1 EIF2S2 ERBB2 GDF9 GSTM4 HAP1 HLA-DQA1 HSPE1 ING5 KAT5 LRIF1 MPHOSPH6 NACA PCDHA4 PHF10 PIN1 PNP PRNP RAP1B RBM48 RCC1 SAT1 SETDB1 SMN1 SNCA STX5 TCF21 TK1 TMSB4X TOE1 TSC22D1 UTP14A VIM ZNF24	9 interacting genes: APLP1 CELSR2 L3MBTL2 LIG4 SETDB1 STAM2 UNC119 UTP14A VAV2
Entrez ID		333	55274
HPRD ID		00102	11428
Ensembl ID		ENSG00000105290	ENSG00000130024
Uniprot IDs		P51693	Q8WUB8
PDB IDs		3PMR 3Q7G 3Q7L 3QMK 4RD9 4RDA
Enriched GO Terms of Interacting Partners?
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