TMEM50B and FXYD3

Data Source:
BioGRID (two hybrid)

		TMEM50B	FXYD3
Description		transmembrane protein 50B	FXYD domain containing ion transport regulator 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding	Chloride Channel Activity Sodium Channel Regulator Activity Ion Channel Regulator Activity
	Biological Process	Biological_process Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway	Potassium Ion Transport Sodium Ion Transport Chloride Transport Ion Transmembrane Transport Chloride Transmembrane Transport Regulation Of Cardiac Conduction Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways			Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
Drugs
Diseases
GWAS		Crohn's disease ( 23128233) Educational attainment ( 25201988)
Interacting Genes		21 interacting genes: AMIGO1 BCL2L1 CLRN1 CREB3L1 EDA FAM209A FXYD3 GPR152 GPX8 HLA-DPA1 LEPROTL1 LHFPL5 NCR1 SCN3B SLC10A6 SLC16A13 SLC35C2 TMEM14B TMEM52B TMEM88 TMX2	64 interacting genes: AGR3 ANK1 AQP6 AQP9 BCL2L13 BEST2 CD79A CNR2 CREB3 CREB3L1 CYB5R3 EBP ERG28 ERGIC3 FAM209A FBXL12 FCGR2A FFAR2 GHITM GPR152 GPR37L1 GPR42 GPRC5D IBSP KASH5 KCNN4 LMNA LTC4S MAPK6 MFSD11 MFSD5 MGST1 MTIF3 NR4A1 NUDT3 PLPP6 SCN3B SERBP1 SGPL1 SLC10A1 SLC10A6 SLC16A12 SLC18A1 SLC1A1 SLC30A2 SLC35A1 SLC35B1 SLC35C2 SLC39A2 SPNS3 STRIT1 STX3 TIMM23 TIMMDC1 TLCD1 TMBIM6 TMEM179B TMEM50B TMEM52B TMEM80 TMEM86A TMEM97 TSPO2 XKR3
Entrez ID		757	5349
HPRD ID		10747	05410
Ensembl ID		ENSG00000142188	ENSG00000089356
Uniprot IDs		P56557	Q14802
PDB IDs
Enriched GO Terms of Interacting Partners?
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