FXYD3 and TMEM179B

Data Source:
BioGRID (two hybrid)

		FXYD3	TMEM179B
Description		FXYD domain containing ion transport regulator 3	transmembrane protein 179B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome	Nucleolus Plasma Membrane Integral Component Of Membrane Nuclear Speck Secretory Granule Membrane Azurophil Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Chloride Channel Activity Sodium Channel Regulator Activity Ion Channel Regulator Activity	Protein Binding
	Biological Process	Potassium Ion Transport Sodium Ion Transport Chloride Transport Ion Transmembrane Transport Chloride Transmembrane Transport Regulation Of Cardiac Conduction Regulation Of Sodium Ion Transmembrane Transporter Activity	Neutrophil Degranulation
Pathways		Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS	Neutrophil degranulation
Drugs
Diseases
GWAS			Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		64 interacting genes: AGR3 ANK1 AQP6 AQP9 BCL2L13 BEST2 CD79A CNR2 CREB3 CREB3L1 CYB5R3 EBP ERG28 ERGIC3 FAM209A FBXL12 FCGR2A FFAR2 GHITM GPR152 GPR37L1 GPR42 GPRC5D IBSP KASH5 KCNN4 LMNA LTC4S MAPK6 MFSD11 MFSD5 MGST1 MTIF3 NR4A1 NUDT3 PLPP6 SCN3B SERBP1 SGPL1 SLC10A1 SLC10A6 SLC16A12 SLC18A1 SLC1A1 SLC30A2 SLC35A1 SLC35B1 SLC35C2 SLC39A2 SPNS3 STRIT1 STX3 TIMM23 TIMMDC1 TLCD1 TMBIM6 TMEM179B TMEM50B TMEM52B TMEM80 TMEM86A TMEM97 TSPO2 XKR3	47 interacting genes: ADIPOQ BTN2A2 C1QL4 C2CD2L C3orf52 CCDC167 CCL3L3 CCL4 CCL4L2 CD68 CLCA4 CLCN7 CLDN1 CLDN6 CTXN3 CYB561 DERL3 ERGIC3 FAM163A FATE1 FCER1G FXYD3 GALNT15 GKN1 GPR151 GUCA2A IGFBP5 KRTAP12-2 KTN1 LRP10 LYG1 MARCHF2 MFSD5 MFSD6 PLN SERP2 SLC1A1 SLC22A1 SLC52A1 STX8 TM4SF19 TMEM14A TMEM236 TMEM237 TMEM242 TMEM47 TRARG1
Entrez ID		5349	374395
HPRD ID		05410	14186
Ensembl ID		ENSG00000089356	ENSG00000185475
Uniprot IDs		Q14802	Q7Z7N9
PDB IDs
Enriched GO Terms of Interacting Partners?
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