FXYD3 and SLC39A2

Data Source:
BioGRID (two hybrid)

		FXYD3	SLC39A2
Description		FXYD domain containing ion transport regulator 3	solute carrier family 39 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Membrane Cytoplasmic Vesicle Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Chloride Channel Activity Sodium Channel Regulator Activity Ion Channel Regulator Activity	Zinc Ion Transmembrane Transporter Activity Protein Binding
	Biological Process	Potassium Ion Transport Sodium Ion Transport Chloride Transport Ion Transmembrane Transport Chloride Transmembrane Transport Regulation Of Cardiac Conduction Regulation Of Sodium Ion Transmembrane Transporter Activity	Zinc Ion Transport Zinc Ion Transmembrane Transport
Pathways		Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS	Zinc influx into cells by the SLC39 gene family
Drugs
Diseases
GWAS
Interacting Genes		64 interacting genes: AGR3 ANK1 AQP6 AQP9 BCL2L13 BEST2 CD79A CNR2 CREB3 CREB3L1 CYB5R3 EBP ERG28 ERGIC3 FAM209A FBXL12 FCGR2A FFAR2 GHITM GPR152 GPR37L1 GPR42 GPRC5D IBSP KASH5 KCNN4 LMNA LTC4S MAPK6 MFSD11 MFSD5 MGST1 MTIF3 NR4A1 NUDT3 PLPP6 SCN3B SERBP1 SGPL1 SLC10A1 SLC10A6 SLC16A12 SLC18A1 SLC1A1 SLC30A2 SLC35A1 SLC35B1 SLC35C2 SLC39A2 SPNS3 STRIT1 STX3 TIMM23 TIMMDC1 TLCD1 TMBIM6 TMEM179B TMEM50B TMEM52B TMEM80 TMEM86A TMEM97 TSPO2 XKR3	51 interacting genes: AQP1 AQP6 ARL13B BCL2L2 BTN2A2 C3orf52 C4orf3 CD79A CLCA4 CNR2 COL4A5 COMT CREB3L1 CXCR2 CYB561 EHHADH EMC6 FCER1G FXYD3 FXYD6 GJA8 GPR152 GPR42 KCNAB1 KCNAB2 LY6G6C MFSD6 MS4A13 PLN PNLIPRP1 SEC22A SLC18A1 SLC30A2 SLC30A8 SLC39A1 SLC39A9 SLC66A1 SLC7A1 SSMEM1 ST6GAL2 STATH TMEM107 TMEM14B TMEM229B TMEM237 TMEM54 TMEM60 TMEM86A TRHR UPK1B YIPF6
Entrez ID		5349	29986
HPRD ID		05410	15385
Ensembl ID		ENSG00000089356	ENSG00000165794
Uniprot IDs		Q14802	Q9NP94
PDB IDs
Enriched GO Terms of Interacting Partners?
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