PTTG1IP and SGCB

Data Source:
BioGRID (two hybrid)

		PTTG1IP	SGCB
Description		PTTG1 interacting protein	sarcoglycan beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane Integral Component Of Membrane Extracellular Exosome	Cytoplasm Cytoskeleton Integral Component Of Plasma Membrane Dystrophin-associated Glycoprotein Complex Sarcoglycan Complex Sarcolemma
	Molecular Function	P53 Binding Molecular_function Protein Binding	Protein Binding
	Biological Process	Protein Import Into Nucleus Positive Regulation Of Protein Ubiquitination Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Cellular Protein Catabolic Process	Muscle Organ Development Muscle Fiber Development Cardiac Muscle Cell Development Vascular Associated Smooth Muscle Cell Development
Pathways
Drugs
Diseases			Sarcoglycanopathies, including: Limb-girdle muscular dystrophy (LGMD) 2C; Limb-girdle muscular dystrophy (LGMD) 2D; Limb-girdle muscular dystrophy (LGMD) 2E; Limb-girdle muscular dystrophy (LGMD) 2F Limb-girdle muscular dystrophy (LGMD)
GWAS		Ankylosing spondylitis ( 30946743) Apolipoprotein A1 levels ( 32203549) Delirium ( 29631748) Gamma glutamyl transferase levels ( 29403010) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) High density lipoprotein cholesterol levels ( 29403010) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494 28957414)
Interacting Genes		11 interacting genes: AMIGO1 ATP6AP2 CLEC7A LDLRAD1 PTTG1 RAB4A SGCB SLC22A23 TMEM106C TMPRSS2 TNFSF14	22 interacting genes: ADAM33 ADRA1A APOL3 BRICD5 CLEC7A CMTM5 EHHADH HTR2C LTB4R2 MAL MGST2 NINJ1 PTTG1IP SGCA SGCD SGCG SGCZ SLC52A1 SMIM3 TMEM11 TNF TRIM63
Entrez ID		754	6443
HPRD ID		04807	02942
Ensembl ID		ENSG00000183255	ENSG00000163069
Uniprot IDs		B4DPZ0 P53801	Q16585 Q5U0N0
PDB IDs
Enriched GO Terms of Interacting Partners?
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