PTTG1IP and LDLRAD1

Data Source:
BioGRID (two hybrid)

		PTTG1IP	LDLRAD1
Description		PTTG1 interacting protein	low density lipoprotein receptor class A domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane Integral Component Of Membrane Extracellular Exosome	Integral Component Of Membrane
	Molecular Function	P53 Binding Molecular_function Protein Binding	Protein Binding
	Biological Process	Protein Import Into Nucleus Positive Regulation Of Protein Ubiquitination Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Cellular Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 30946743) Apolipoprotein A1 levels ( 32203549) Delirium ( 29631748) Gamma glutamyl transferase levels ( 29403010) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) High density lipoprotein cholesterol levels ( 29403010) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494 28957414)	Parkinson disease and lewy body pathology ( 25663231)
Interacting Genes		11 interacting genes: AMIGO1 ATP6AP2 CLEC7A LDLRAD1 PTTG1 RAB4A SGCB SLC22A23 TMEM106C TMPRSS2 TNFSF14	34 interacting genes: ADGRG7 ANKRD46 AQP1 BNIP2 BNIP3 BNIP3L CMTM7 CTXN3 CXCL9 EBP EMP3 GIMAP5 GPR25 IGFBP5 LAPTM5 MAL MALL MARCHF2 NINJ2 OLFM4 PLN PLPP6 PTTG1IP SEC22A SLC1A1 SLC41A2 TMEM147 TMEM190 TMEM218 TMEM79 UNC93B1 VAMP4 VTI1B ZFPL1
Entrez ID		754	388633
HPRD ID		04807	17372
Ensembl ID		ENSG00000183255	ENSG00000203985
Uniprot IDs		B4DPZ0 P53801	Q5T700
PDB IDs
Enriched GO Terms of Interacting Partners?
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