TSPO and CLEC10A

Data Source:
BioGRID (two hybrid)

		TSPO	CLEC10A
Description		translocator protein	C-type lectin domain containing 10A
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Cytosol Integral Component Of Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Androgen Binding Protein Binding Benzodiazepine Receptor Activity Cholesterol Binding Ion Channel Binding	Protein Binding Carbohydrate Binding
	Biological Process	Protein Targeting To Mitochondrion C21-steroid Hormone Biosynthetic Process Heme Biosynthetic Process Anion Transport Chloride Transport Lipid Transport Aging Steroid Metabolic Process Glial Cell Migration Response To Manganese Ion Response To Vitamin B1 Positive Regulation Of Necrotic Cell Death Peripheral Nervous System Axon Regeneration Adrenal Gland Development Negative Regulation Of Protein Ubiquitination Regulation Of Cholesterol Transport Response To Progesterone Negative Regulation Of Tumor Necrosis Factor Production Response To Testosterone Regulation Of Cell Population Proliferation Response To Drug Positive Regulation Of Apoptotic Process Negative Regulation Of Nitric Oxide Biosynthetic Process Behavioral Response To Pain Regulation Of Steroid Biosynthetic Process Positive Regulation Of Mitochondrial Depolarization Positive Regulation Of Calcium Ion Transport Contact Inhibition Positive Regulation Of Glial Cell Proliferation Negative Regulation Of Glial Cell Proliferation Cellular Response To Lipopolysaccharide Cellular Response To Zinc Ion Cellular Hypotonic Response Maintenance Of Protein Location In Mitochondrion Negative Regulation Of Autophagy Of Mitochondrion Negative Regulation Of ATP Metabolic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process	Stimulatory C-type Lectin Receptor Signaling Pathway Adaptive Immune Response Endocytosis Innate Immune Response
Pathways		Pregnenolone biosynthesis	Dectin-2 family
Drugs		Chlormezanone Zopiclone
Diseases
GWAS		Metabolite levels ( 23823483) Monocyte count ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) White blood cell count ( 32888494)	Carotid intima media thickness x smoking interaction ( 32117412) GIP levels in response to oral glucose tolerance test (120 minutes) ( 29093273) Neurological blood protein biomarker levels ( 31320639)
Interacting Genes		17 interacting genes: AMIGO1 CLEC10A CREB3L1 DBI FAM209A FCER1G ICAM3 KCNF1 LEUTX LHFPL5 LYPD5 MEOX2 NCR3LG1 PVR TMEM14B TMEM9 TSPOAP1	24 interacting genes: ACSF2 ADIPOQ APOD BET1 C3orf52 CLN6 FMO3 FXYD6 GIMAP1 MALL NAPB PEX16 PRAF2 SEC22A SLC38A7 SMCO4 TMEM218 TNF TRARG1 TSPO UNC50 VSTM1 ZDHHC15 ZFPL1
Entrez ID		706	10462
HPRD ID		15913	12076
Ensembl ID		ENSG00000100300	ENSG00000132514
Uniprot IDs		O76068 P30536	J3KR22 Q8IUN9
PDB IDs			6PUV 6PY1
Enriched GO Terms of Interacting Partners?
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