TSPO and TSPOAP1

Data Source:
BioGRID (pull down)
HPRD (in vitro, two hybrid)

		TSPO	TSPOAP1
Description		translocator protein	TSPO associated protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Cytosol Integral Component Of Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Cytoplasm Mitochondrion Cytosol Calyx Of Held Glutamatergic Synapse
	Molecular Function	Androgen Binding Protein Binding Benzodiazepine Receptor Activity Cholesterol Binding Ion Channel Binding	Protein Binding Benzodiazepine Receptor Binding Voltage-gated Calcium Channel Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Levels
	Biological Process	Protein Targeting To Mitochondrion C21-steroid Hormone Biosynthetic Process Heme Biosynthetic Process Anion Transport Chloride Transport Lipid Transport Aging Steroid Metabolic Process Glial Cell Migration Response To Manganese Ion Response To Vitamin B1 Positive Regulation Of Necrotic Cell Death Peripheral Nervous System Axon Regeneration Adrenal Gland Development Negative Regulation Of Protein Ubiquitination Regulation Of Cholesterol Transport Response To Progesterone Negative Regulation Of Tumor Necrosis Factor Production Response To Testosterone Regulation Of Cell Population Proliferation Response To Drug Positive Regulation Of Apoptotic Process Negative Regulation Of Nitric Oxide Biosynthetic Process Behavioral Response To Pain Regulation Of Steroid Biosynthetic Process Positive Regulation Of Mitochondrial Depolarization Positive Regulation Of Calcium Ion Transport Contact Inhibition Positive Regulation Of Glial Cell Proliferation Negative Regulation Of Glial Cell Proliferation Cellular Response To Lipopolysaccharide Cellular Response To Zinc Ion Cellular Hypotonic Response Maintenance Of Protein Location In Mitochondrion Negative Regulation Of Autophagy Of Mitochondrion Negative Regulation Of ATP Metabolic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process	C21-steroid Hormone Biosynthetic Process Neurotransmitter Secretion Neuromuscular Synaptic Transmission Biological_process Glutamate Secretion Regulation Of Presynaptic Cytosolic Calcium Ion Concentration
Pathways		Pregnenolone biosynthesis	Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Pregnenolone biosynthesis Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle
Drugs		Chlormezanone Zopiclone
Diseases
GWAS		Metabolite levels ( 23823483) Monocyte count ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) White blood cell count ( 32888494)
Interacting Genes		17 interacting genes: AMIGO1 CLEC10A CREB3L1 DBI FAM209A FCER1G ICAM3 KCNF1 LEUTX LHFPL5 LYPD5 MEOX2 NCR3LG1 PVR TMEM14B TMEM9 TSPOAP1	19 interacting genes: ANKRD11 ARNT2 BEND5 CACNA1A CADPS2 CEP76 DISC1 DLGAP2 DLX2 GPRASP2 KHDRBS1 KIF1A MVP NDE1 RAPGEF4 REL TCF4 TSC22D4 TSPO
Entrez ID		706	9256
HPRD ID		15913	09832
Ensembl ID		ENSG00000100300	ENSG00000005379
Uniprot IDs		O76068 P30536	A7E2C5 B2RUT8 B7ZVZ7 O95153 X5DQQ3
PDB IDs
Enriched GO Terms of Interacting Partners?
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