CLEC10A and FMO3

Data Source:
BioGRID (two hybrid)

		CLEC10A	FMO3
Description		C-type lectin domain containing 10A	flavin containing dimethylaniline monoxygenase 3
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Endoplasmic Reticulum Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Carbohydrate Binding	Monooxygenase Activity N,N-dimethylaniline Monooxygenase Activity Protein Binding Trimethylamine Monooxygenase Activity Flavin Adenine Dinucleotide Binding NADP Binding
	Biological Process	Stimulatory C-type Lectin Receptor Signaling Pathway Adaptive Immune Response Endocytosis Innate Immune Response	Xenobiotic Metabolic Process
Pathways		Dectin-2 family	FMO oxidises nucleophiles Defective FMO3 causes Trimethylaminuria (TMAU)
Drugs
Diseases
GWAS		Carotid intima media thickness x smoking interaction ( 32117412) GIP levels in response to oral glucose tolerance test (120 minutes) ( 29093273) Neurological blood protein biomarker levels ( 31320639)	Blood metabolite levels ( 24816252) Lentiform nucleus volume ( 22903471)
Interacting Genes		24 interacting genes: ACSF2 ADIPOQ APOD BET1 C3orf52 CLN6 FMO3 FXYD6 GIMAP1 MALL NAPB PEX16 PRAF2 SEC22A SLC38A7 SMCO4 TMEM218 TNF TRARG1 TSPO UNC50 VSTM1 ZDHHC15 ZFPL1	4 interacting genes: CLEC10A CREB3 SACM1L SGSM3
Entrez ID		10462	2328
HPRD ID		12076	00633
Ensembl ID		ENSG00000132514	ENSG00000007933
Uniprot IDs		J3KR22 Q8IUN9	A0A024R8Z4 B7Z3M2 B7Z543 P31513 Q53FW5
PDB IDs		6PUV 6PY1
Enriched GO Terms of Interacting Partners?
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