TAF9 and KPNA6

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TAF9	KPNA6
Description		TATA-box binding protein associated factor 9	karyopherin subunit alpha 6
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GO Annotations	Cellular Component	SAGA Complex PCAF Complex Nucleus Nucleoplasm Transcription Factor TFIID Complex STAGA Complex Transcription Factor TFTC Complex Pre-snoRNP Complex MLL1 Complex	Nucleus Nucleoplasm Cytoplasm Membrane Host Cell
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding P53 Binding DNA Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Activating Transcription Factor Binding Protein Heterodimerization Activity ATPase Binding C2H2 Zinc Finger Domain Binding	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity
	Biological Process	Box C/D SnoRNP Assembly Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Cellular Response To DNA Damage Stimulus Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process SnRNA Transcription By RNA Polymerase II Negative Regulation Of Apoptotic Process Histone H3 Acetylation Positive Regulation Of Transcription By RNA Polymerase II Protein Stabilization Positive Regulation Of Response To Cytokine Stimulus Response To Interleukin-1 Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator	NLS-bearing Protein Import Into Nucleus Viral Genome Replication Mitigation Of Host Defenses By Symbiont Positive Regulation Of Transcription By RNA Polymerase II Maternal Process Involved In Female Pregnancy Entry Of Viral Genome Into Host Nucleus Through Nuclear Pore Complex Via Importin Positive Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Viral Life Cycle
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome HATs acetylate histones RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS			Body mass index ( 26426971)
Interacting Genes		57 interacting genes: AHR ANK2 APP CEBPB CIITA COIL DRAP1 EEF1A1 ELF3 FBL FBLN1 FEZ1 GALNT6 GLI1 GLI2 GLI3 GTF2B H3-4 HCFC1 HNF4A HSF1 KLF6 KMT2A KPNA1 KPNA6 LAMTOR5 MAGEC2 MYC NCOA2 NCOR1 NDRG1 NFATC2 NR1D2 NUFIP1 PJA1 RBM48 RELA RNF138 RPS14 RPS24 RUVBL1 RUVBL2 SF3B3 TAF1 TAF10 TAF11 TAF12 TAF2 TAF4 TAF5 TAF6 TAF6L TAF7 TAF8 TBCA TP53 UBA1	37 interacting genes: ANKRD11 ANP32A ANP32B ARNT BRCA1 CDKN1B CREBBP CSE1L DCPS EPAS1 FAM90A1 FRG1BP GEMIN2 HIF1A IL1A JRK KAT5 KEAP1 KPNB1 LMNA LMNB1 MAGED1 NMNAT1 NOP2 NUP50 POLR3C POM121 POU6F2 RAC1 RELB RNMT SKP2 SMARCB1 STAT1 STAT3 TAF9 ZNF131
Entrez ID		6880	23633
HPRD ID		15983	09465
Ensembl ID		ENSG00000273841	ENSG00000025800
Uniprot IDs		Q16594	O60684
PDB IDs		6F3T 6MZC 6MZD 6MZL 6MZM	4UAD
Enriched GO Terms of Interacting Partners?
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