TACC1 and SNRPG

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		TACC1	SNRPG
Description		transforming acidic coiled-coil containing protein 1	small nuclear ribonucleoprotein polypeptide G
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Organizing Center Cytosol Membrane Midbody	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP U7 SnRNP U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome SMN-Sm Protein Complex P Granule U4/U6 X U5 Tri-snRNP Complex U2-type Prespliceosome U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal Tri-snRNP Complex Ribonucleoprotein Complex
	Molecular Function	Protein Binding Nuclear Receptor Binding Estrogen Receptor Binding Nuclear Receptor Coactivator Activity Glucocorticoid Receptor Binding Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Retinoid X Receptor Binding Thyroid Hormone Receptor Binding	RNA Binding Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Cell Population Proliferation Cerebral Cortex Development Positive Regulation Of Transcription, DNA-templated Cell Division	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription Histone MRNA Metabolic Process RNA Splicing Import Into Nucleus
Pathways			SLBP independent Processing of Histone Pre-mRNAs snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Chronic mountain sickness ( 31417607) Midgestational circulating levels of PBDEs ( 28235828)	Acne (severe) ( 24927181) Male-pattern baldness ( 28196072)
Interacting Genes		20 interacting genes: AURKA AURKB BTRC ERCC4 FAM50B HTT ITSN2 KAT2A KDM1A LSM7 MEMO1 SH2D4A SNRPG STX5 TDRD7 THAP12 THRA YEATS4 ZFHX3 ZNF48	21 interacting genes: CEP126 CLNS1A COPS6 CRMP1 DDIT4L DDX20 ERG28 FHL3 GDF9 GEMIN5 GEMIN6 IL7R LSM3 PEA15 SMN2 SNRPD3 SNRPE SNRPF TACC1 TCL1B TLE1
Entrez ID		6867	6637
HPRD ID		10391	04646
Ensembl ID		ENSG00000147526	ENSG00000143977
Uniprot IDs		E7EVI4 O75410 Q5HYH0	C9JVQ0 F5H013 P62308 Q49AN9
PDB IDs			3CW1 3JCR 3PGW 4F7U 4PJO 4V98 4WZJ 5MQF 5O9Z 5XJC 5XJL 5XJQ 5XJR 5XJT 5XJU 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6V4X 6Y53 6Y5Q 7A5P
Enriched GO Terms of Interacting Partners?
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