TACC1 and SH2D4A

Data Source:
BioGRID (two hybrid)

		TACC1	SH2D4A
Description		transforming acidic coiled-coil containing protein 1	SH2 domain containing 4A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Organizing Center Cytosol Membrane Midbody	Cytoplasm Cytosol
	Molecular Function	Protein Binding Nuclear Receptor Binding Estrogen Receptor Binding Nuclear Receptor Coactivator Activity Glucocorticoid Receptor Binding Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Retinoid X Receptor Binding Thyroid Hormone Receptor Binding	Protein Binding Phosphatase Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Cell Population Proliferation Cerebral Cortex Development Positive Regulation Of Transcription, DNA-templated Cell Division	Negative Regulation Of Phosphatase Activity
Pathways
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Chronic mountain sickness ( 31417607) Midgestational circulating levels of PBDEs ( 28235828)	Smooth-surface caries ( 24556642) Urate levels in overweight individuals ( 25811787) Urinary albumin excretion rate in type 1 diabetes ( 24595857)
Interacting Genes		20 interacting genes: AURKA AURKB BTRC ERCC4 FAM50B HTT ITSN2 KAT2A KDM1A LSM7 MEMO1 SH2D4A SNRPG STX5 TDRD7 THAP12 THRA YEATS4 ZFHX3 ZNF48	74 interacting genes: ALAS1 ARC BLOC1S2 CADPS CASK CCDC172 CCDC88B CDR2 CDR2L CEP70 CEP76 CFAP53 DBNL FCHO1 FCHSD2 FSD2 GOLGA2 GOLGA6L9 GPRASP2 GRAMD4 GRAP2 GRB2 HCLS1 HMBOX1 HOOK2 HSF2BP IKZF1 KRT40 LDOC1 LZTS2 MAGEA11 MAGEA6 MBD3L1 MEOX2 MORN3 MRFAP1 MTUS2 NECAB2 NINL NUTM1 OLIG1 PDE4DIP PICK1 PLEKHG4 PNMA1 PPP1CB PRKAR1B PSTPIP1 RINT1 SH3GL1 SH3RF1 SKAP1 SORBS2 SORBS3 SPAG5 STAM2 STX11 TACC1 TFIP11 TRAF2 TRIM23 TRIM27 TRIML2 TTC19 UBXN11 USHBP1 VPS52 WWOX YPEL2 YPEL3 ZBTB16 ZMYND12 ZNF655 ZNF774
Entrez ID		6867	63898
HPRD ID		10391	08340
Ensembl ID		ENSG00000147526	ENSG00000104611
Uniprot IDs		E7EVI4 O75410 Q5HYH0	Q9H788
PDB IDs
Enriched GO Terms of Interacting Partners?
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