TACC1 and ZNF48

Data Source:
BioGRID (two hybrid)

		TACC1	ZNF48
Description		transforming acidic coiled-coil containing protein 1	zinc finger protein 48
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Organizing Center Cytosol Membrane Midbody	Nucleus
	Molecular Function	Protein Binding Nuclear Receptor Binding Estrogen Receptor Binding Nuclear Receptor Coactivator Activity Glucocorticoid Receptor Binding Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Retinoid X Receptor Binding Thyroid Hormone Receptor Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Cell Population Proliferation Cerebral Cortex Development Positive Regulation Of Transcription, DNA-templated Cell Division	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Chronic mountain sickness ( 31417607) Midgestational circulating levels of PBDEs ( 28235828)	Brain morphology (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		20 interacting genes: AURKA AURKB BTRC ERCC4 FAM50B HTT ITSN2 KAT2A KDM1A LSM7 MEMO1 SH2D4A SNRPG STX5 TDRD7 THAP12 THRA YEATS4 ZFHX3 ZNF48	18 interacting genes: APOBEC3C BYSL CEP55 EIF3E FNDC11 GOLGA2 GOLGA6L9 HOOK2 MORF4L2 MTUS2 OSBPL3 PRPF31 SF3B4 TACC1 TLE5 TRIM41 ZNF774 ZNF792
Entrez ID		6867	197407
HPRD ID		10391	15836
Ensembl ID		ENSG00000147526	ENSG00000180035
Uniprot IDs		E7EVI4 O75410 Q5HYH0	A0A087WVT1 Q96MX3
PDB IDs
Enriched GO Terms of Interacting Partners?
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