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SRF and MYOD1
Data Source:
HPRD
(in vitro, in vivo, two hybrid)
SRF
MYOD1
Description
serum response factor
myogenic differentiation 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Chromatin
Euchromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Myofibril
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Transcription Factor Binding
Serum Response Element Binding
Chromatin DNA Binding
Protein Homodimerization Activity
Histone Deacetylase Binding
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Primary MiRNA Binding
Sequence-specific Double-stranded DNA Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
RNA Polymerase II Activating Transcription Factor Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Chromatin Binding
Protein Binding
Chromatin DNA Binding
Ubiquitin Protein Ligase Binding
Nuclear Hormone Receptor Binding
Protein Homodimerization Activity
E-box Binding
Sequence-specific Double-stranded DNA Binding
Promoter-specific Chromatin Binding
Biological Process
Branching Involved In Blood Vessel Morphogenesis
Response To Hypoxia
Mesoderm Formation
Neuron Migration
Trophectodermal Cell Differentiation
Heart Looping
Morphogenesis Of An Epithelial Sheet
Cell Migration Involved In Sprouting Angiogenesis
Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Myocardial Precursor Cell Differentiation
Regulation Of Transcription By RNA Polymerase II
Cell-matrix Adhesion
Heart Development
Long-term Memory
Negative Regulation Of Cell Population Proliferation
Associative Learning
Response To Toxic Substance
Response To Hormone
Epithelial Structure Maintenance
Positive Regulation Of Transcription Via Serum Response Element Binding
Hippocampus Development
Tangential Migration From The Subventricular Zone To The Olfactory Bulb
Actin Cytoskeleton Organization
Regulation Of Cell Adhesion
Platelet Activation
Platelet Formation
Negative Regulation Of Cell Migration
Thyroid Gland Development
Neuron Projection Development
Regulation Of Water Loss Via Skin
Response To Cytokine
Megakaryocyte Development
Dorsal Aorta Morphogenesis
Stress Fiber Assembly
Skin Morphogenesis
Positive Thymic T Cell Selection
Sarcomere Organization
Positive Regulation Of Cell Differentiation
Positive Regulation Of Axon Extension
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Smooth Muscle Contraction
Positive Regulation Of Transcription By Glucose
Muscle Cell Cellular Homeostasis
Thymus Development
Developmental Growth
Neuron Development
Erythrocyte Development
Positive Regulation Of DNA-binding Transcription Factor Activity
Regulation Of Smooth Muscle Cell Differentiation
Positive Regulation Of Filopodium Assembly
Cardiac Myofibril Assembly
Angiogenesis Involved In Wound Healing
Hematopoietic Stem Cell Differentiation
Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter
Long-term Synaptic Depression
Face Development
Heart Trabecula Formation
Lung Morphogenesis
Bronchus Cartilage Development
Trachea Cartilage Development
Cardiac Vascular Smooth Muscle Cell Differentiation
Eyelid Development In Camera-type Eye
Lung Smooth Muscle Development
Bicellular Tight Junction Assembly
Cellular Response To Glucose Stimulus
Primitive Streak Formation
Epithelial Cell-cell Adhesion
Cellular Senescence
Negative Regulation Of Amyloid-beta Clearance
Negative Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Regulation Of Alternative MRNA Splicing, Via Spliceosome
Regulation Of Transcription By RNA Polymerase II
Protein Phosphorylation
Muscle Organ Development
Myoblast Fate Determination
Skeletal Muscle Tissue Development
Myoblast Fusion
Cellular Response To Starvation
Myotube Cell Development
Myotube Differentiation Involved In Skeletal Muscle Regeneration
Negative Regulation Of Chromatin Binding
Skeletal Muscle Cell Differentiation
Muscle Cell Fate Commitment
Positive Regulation Of Skeletal Muscle Tissue Regeneration
Regulation Of RNA Splicing
Skeletal Muscle Fiber Adaptation
Histone H3 Acetylation
Histone H4 Acetylation
Positive Regulation Of Myoblast Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Skeletal Muscle Fiber Development
Positive Regulation Of Skeletal Muscle Fiber Development
Positive Regulation Of Binding
Positive Regulation Of Muscle Cell Differentiation
Cellular Response To Tumor Necrosis Factor
Cellular Response To Glucocorticoid Stimulus
Cellular Response To Estradiol Stimulus
Cellular Response To Oxygen Levels
Positive Regulation Of Myoblast Fusion
Positive Regulation Of SnRNA Transcription By RNA Polymerase II
Negative Regulation Of Myoblast Proliferation
Pathways
RHO GTPases Activate Formins
NGF-stimulated transcription
NGF-stimulated transcription
Estrogen-dependent nuclear events downstream of ESR-membrane signaling
Myogenesis
Myogenesis
Drugs
Diseases
GWAS
Body mass index (
26426971
)
Metabolite levels (
23823483
)
Night sleep phenotypes (
27126917
)
Interacting Genes
71 interacting genes:
ALDH3A1
ATF6
BARX2
CAMK2A
CASP3
CASP6
CASP7
CASP8
CASP9
CD63
CEBPB
CIRBP
CREB1
CREBBP
CRIP2
CSNK2A1
ELK1
ELK4
ETV4
FHL1
FHL2
FHL3
FHL5
FLI1
FOXG1
FOXK1
GATA4
GTF2F1
GTF2I
HDAC4
HMGA1
HOPX
KAT5
KDM6A
MAPKAPK2
MINPP1
MRTFA
MRTFB
MYOCD
MYOD1
MYOG
NCOA1
NCOA6
NCOR2
NFKB1
NFYA
NKX2-3
NKX2-5
NKX3-1
OGT
PML
PRKDC
PRRX1
PYCARD
RARA
REL
RELA
RPS6KA1
RXRA
RXRG
SHBG
SP1
SRC
SRFBP1
SSRP1
TCF3
TEAD1
TRIM63
TRIP4
UBE2I
ZIC3
67 interacting genes:
AP1M1
ASCL3
BHLHA15
BHLHE40
BHLHE41
C2orf88
CALM1
CALM2
CALM3
CARM1
CDC34
CDK2
CDK4
CDKN1C
CIB2
CREBBP
CSRP3
ELSPBP1
EP300
EXOC3L1
FBXO32
FIGLA
HAND1
HDAC1
HEY1
HSP90AA1
ID1
ID2
ID3
ID4
IFRD1
IGFN1
JUN
KAT2B
KAT5
KPNA3
LMO4
MDFI
MEF2A
MEF2C
MOS
MYOCD
NCOR1
NCOR2
NR2F2
PHB2
POLR2G
PRKCA
PRMT5
PSMD4
PSME2
RB1
RORA
RUNX1
RXRA
SETD3
SMAD3
SMAD4
SMAD7
SP1
SRF
STAT3
SUV39H1
TCF21
TCF3
TCF4
TWIST1
Entrez ID
6722
4654
HPRD ID
02788
01166
Ensembl ID
ENSG00000112658
ENSG00000129152
Uniprot IDs
A0A024RD16
B4DU24
P11831
P15172
PDB IDs
1HBX
1K6O
1SRS
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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