SMARCC2 and PHYHIP

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SMARCC2	PHYHIP
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2	phytanoyl-CoA 2-hydroxylase interacting protein
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex	Cytoplasm
	Molecular Function	Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding Histone Binding	Protein Tyrosine Kinase Binding
	Biological Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development ATP-dependent Chromatin Remodeling Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated	Protein Localization
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS		Asthma ( 31619474) Refractive error ( 32231278)	Hypertriglyceridemia ( 23505323)
Interacting Genes		26 interacting genes: ARRB2 ATXN1 ATXN1L BAZ1B CSNK2A1 EWSR1 FUS GATA1 IFTAP ITCH ITSN1 KLF1 KRT27 MCPH1 NOVA1 PEX14 PHYHIP POLR2C RAB1B RELB SMARCB1 SP1 SRGAP3 TAF15 TERF1 TERF2IP	24 interacting genes: ADGRB1 COPS6 DYRK1A EEF1A1 ERG28 FAM131A HDAC11 HNRNPA1 MAGED4B MED8 METTL18 NDRG1 NDUFV3 NFE2 PHYH PNPLA2 PPIE PRMT5 S100A13 SMARCC2 SUPT5H TTR WDR89 ZZEF1
Entrez ID		6601	9796
HPRD ID		03437	16345
Ensembl ID		ENSG00000139613	ENSG00000168490
Uniprot IDs		A0A024RB22 F8VXC8 Q8TAQ2	Q92561
PDB IDs		6KAG 6LTH 6LTJ
Enriched GO Terms of Interacting Partners?
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